The human skeleton has remarkable regenerative properties, being one of the few
structures in the body that can heal by recreating its normal cellular composition, orientation …

Bone homeostasis depends on the resorption of bones by osteoclasts and formation of
bones by the osteoblasts. Imbalance of this tightly coupled process can cause diseases …

Objectives The present study aimed to investigate whether exosomes derived from miR‐375‐
overexpressing human adipose mesenchymal stem cells (hASCs) could enhance bone …

The success of regenerative medicine in various clinical applications depends on the
appropriate selection of the source of mesenchymal stem cells (MSCs). Indeed, the source …

Mesenchymal stem cells (MSCs), a non-hematopoietic stem cell population first discovered
in bone marrow, are multipotent cells capable of differentiating into mature cells of several …

Osteoporosis is one of the most common skeletal disorders caused by the imbalance
between bone formation and resorption, resulting in quantitative loss of bone tissue. Since …

Long non-coding RNAs (lncRNAs) have emerged as promising novel modulators during
osteogenesis in mesenchymal stem cells (MSCs). Enhanced SATB2 has been …

Emerging evidence indicates that osteoclasts direct osteoblastic bone formation. MicroRNAs
(miRNAs) have a crucial role in regulating osteoclast and osteoblast function. However …

In elderly people particularly in postmenopausal women, inadequate bone formation by
osteoblasts originating from bone marrow mesenchymal stem cells (BMSCs) for …

Periodontitis is a chronic inflammatory disease of the gums. The incidence of periodontitis is
increasing all over the world. In patients with periodontitis, there is gradual destruction of the …