The impact of centromeres on spatial genome architecture
The development of new technologies and experimental techniques is enabling researchers
to see what was once unable to be seen. For example, the centromere was first seen as the …
to see what was once unable to be seen. For example, the centromere was first seen as the …
Targeting of γ-tubulin complexes to microtubule organizing centers: conservation and divergence
T Lin, A Neuner, E Schiebel - Trends in cell biology, 2015 - cell.com
Organisms with closed or open mitosis have differentially evolved various gamma-tubulin
complex (γ-TuC) recruiting factors to organize diverse cellular microtubule (MT) arrays …
complex (γ-TuC) recruiting factors to organize diverse cellular microtubule (MT) arrays …
Analysis of the Genome and Transcriptome of Cryptococcus neoformans var. grubii Reveals Complex RNA Expression and Microevolution Leading to Virulence …
G Janbon, KL Ormerod, D Paulet, EJ Byrnes III… - PLoS …, 2014 - journals.plos.org
Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …
The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis
IM Dambuza, T Drake, A Chapuis, X Zhou… - PLoS …, 2018 - journals.plos.org
Fungal cells change shape in response to environmental stimuli, and these morphogenic
transitions drive pathogenesis and niche adaptation. For example, dimorphic fungi switch …
transitions drive pathogenesis and niche adaptation. For example, dimorphic fungi switch …
Early diverging fungus Mucor circinelloides lacks centromeric histone CENP-A and displays a mosaic of point and regional centromeres
Centromeres are rapidly evolving across eukaryotes, despite performing a conserved
function to ensure high-fidelity chromosome segregation. CENP-A chromatin is a hallmark of …
function to ensure high-fidelity chromosome segregation. CENP-A chromatin is a hallmark of …
RNAi is a critical determinant of centromere evolution in closely related fungi
V Yadav, S Sun, RB Billmyre… - Proceedings of the …, 2018 - National Acad Sciences
The centromere DNA locus on a eukaryotic chromosome facilitates faithful chromosome
segregation. Despite performing such a conserved function, centromere DNA sequence as …
segregation. Despite performing such a conserved function, centromere DNA sequence as …
Histone modifications rather than the novel regional centromeres of Zymoseptoria tritici distinguish core and accessory chromosomes
K Schotanus, JL Soyer, LR Connolly… - Epigenetics & …, 2015 - Springer
Background Supernumerary chromosomes have been found in many organisms. In fungi,
these “accessory” or “dispensable” chromosomes are present at different frequencies in …
these “accessory” or “dispensable” chromosomes are present at different frequencies in …
The Cyclin Cln1 Controls Polyploid Titan Cell Formation following a Stress-Induced G2 Arrest in Cryptococcus
The pathogenic yeast Cryptococcus neoformans produces polyploid titan cells in response
to the host lung environment that are critical for host adaptation and subsequent disease …
to the host lung environment that are critical for host adaptation and subsequent disease …
Expansion microscopy reveals characteristic ultrastructural features of pathogenic budding yeast species
Candida albicans is the most prevalent fungal pathogen associated with candidemia.
Similar to other fungi, the complex life cycle of C. albicans has been challenging to study …
Similar to other fungi, the complex life cycle of C. albicans has been challenging to study …
Fungal genome and mating system transitions facilitated by chromosomal translocations involving intercentromeric recombination
Species within the human pathogenic Cryptococcus species complex are major threats to
public health, causing approximately 1 million annual infections globally. Cryptococcus …
public health, causing approximately 1 million annual infections globally. Cryptococcus …