Congenital adrenal hyperplasia—current insights in pathophysiology, diagnostics, and management

HL Claahsen-van der Grinten, PW Speiser… - Endocrine …, 2022 - academic.oup.com
Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders affecting
cortisol biosynthesis. Reduced activity of an enzyme required for cortisol production leads to …

Adrenal insufficiency

ES Husebye, SH Pearce, NP Krone, O Kämpe - The Lancet, 2021 - thelancet.com
Adrenal insufficiency can arise from a primary adrenal disorder, secondary to
adrenocorticotropic hormone deficiency, or by suppression of adrenocorticotropic hormone …

Circulating testosterone as the hormonal basis of sex differences in athletic performance

DJ Handelsman, AL Hirschberg, S Bermon - Endocrine reviews, 2018 - academic.oup.com
Elite athletic competitions have separate male and female events due to men's physical
advantages in strength, speed, and endurance so that a protected female category with …

Hypokalemia: a clinical update

E Kardalas, SA Paschou, P Anagnostis… - Endocrine …, 2018 - ec.bioscientifica.com
Hypokalemia is a common electrolyte disturbance, especially in hospitalized patients. It can
have various causes, including endocrine ones. Sometimes, hypokalemia requires urgent …

Sex and gender differences in pain

NR Osborne, KD Davis - International Review of Neurobiology, 2022 - Elsevier
Chronic pain affects 20% of adults and is one of the leading causes of disability worldwide.
Women and girls are disproportionally affected by chronic pain. About half of chronic pain …

Sex/gender differences in cognitive abilities

S Kheloui, S Jacmin-Park, O Larocque, P Kerr… - Neuroscience & …, 2023 - Elsevier
Sex/gender differences in cognitive sciences are riddled by conflicting perspectives. At the
center of debates are clinical, social, and political perspectives. Front and center …

Congenital adrenal hyperplasia due to 21-hydroxylase deficiency

DP Merke, RJ Auchus - New England Journal of Medicine, 2020 - Mass Medical Soc
CAH Due to 21-Hydroxylase Deficiency Congenital adrenal hyperplasia, a common
autosomal recessive disorder, is potentially life-threatening in its classic form and may be …

Management of endocrine disease: diagnosis and management of the patient with non-classic CAH due to 21-hydroxylase deficiency

A Nordenström, H Falhammar - European journal of …, 2019 - academic.oup.com
Non-classic congenital adrenal hyperplasia (NCAH) is a relatively common disorder
regardless of ethnicity, but most cases are never diagnosed, especially in males. A baseline …

[HTML][HTML] Role of insulin and insulin resistance in androgen excess disorders

K Unluhizarci, Z Karaca, F Kelestimur - World journal of diabetes, 2021 - ncbi.nlm.nih.gov
Insulin has complex effects on cell growth, metabolism and differentiation, and these effects
are mediated by a cell-surface bound receptor and eventually a cascade of intracellular …

Phase 3 Trial of Crinecerfont in Adult Congenital Adrenal Hyperplasia

RJ Auchus, O Hamidi, R Pivonello… - … England Journal of …, 2024 - Mass Medical Soc
Background Adrenal insufficiency in patients with classic 21-hydroxylase deficiency
congenital adrenal hyperplasia (CAH) is treated with glucocorticoid replacement therapy …