Pathogenic role of fibrinogen in the neuropathology of multiple sclerosis: a tale of sorrows and fears

M Alruwaili, HM Al-Kuraishy, A Alexiou… - Neurochemical …, 2023 - Springer
Multiple sclerosis (MS) is an autoimmune demyelinating neurodegenerative disease of the
central nervous system (CNS) due to injury of the myelin sheath by immune cells. The …

[HTML][HTML] Fibrinogen-like protein 2 in inflammatory diseases: a future therapeutic target

L Fu, Z Liu, Y Liu - International Immunopharmacology, 2023 - Elsevier
Abstract Fibrinogen-like protein 2 (FGL2), a member of the fibrinogen family, exists as a
membrane-bound protein with immune-associated coagulation activity and a soluble form …

Proteomic analysis and experimental validation reveal the blood–brain barrier protective of Huanshaodan in the treatment of SAMP8 mouse model of Alzheimer's …

Y Su, N Liu, P Wang, C Shang, R Sun, J Ma, Z Li… - Chinese Medicine, 2024 - Springer
Background Huanshaodan (HSD) is a Chinese Herbal Compound which has a definite
clinical effect on Alzheimer's disease (AD), however, the underlying mechanism remains …

Effect of Alkaline Mineral Complex Buffer Supplementation on Rumen Fermentation, Rumen Microbiota and Rumen Epithelial Transcriptome of Newborn Calves

X Wang, C Guo, X Xu, L Zhang, S Li, D Dai, W Du - Fermentation, 2023 - mdpi.com
Alkaline mineral complex buffer can improve rumen fermentation and affect the rumen
microbiota of dairy cows. Here, we studied the effects of alkaline mineral complex buffer on …

Serum Soluble Fibrinogen-Like Protein 2 Estimates Increased T-Helper 2 Cytokine, Elevated Disease Severity, and Unfavorable Outcomes in Allergic Rhinitis Patients

X Qian, D Li, Y Zhang, T Su… - Annals of Otology …, 2024 - journals.sagepub.com
Objective: Soluble fibrinogen-like protein 2 (sFGL2) may be involved in the pathology and
progression of allergic rhinitis (AR) through regulating T-helper (Th) 2 cell response. This …

Potential clinical value of fibrinogen-like protein 1 as a serum biomarker for the identification of diabetic cardiomyopathy

Y Liu, M Wang, JB Su, X Fu, GL Zheng, S Guo… - Scientific Reports, 2024 - nature.com
Diabetic individuals with diabetic cardiomyopathy (DbCM) present with abnormal
myocardial structure and function. DbCM cannot be accurately diagnosed due to the lack of …

Clonorchis sinensis infection contributes to hepatocellular carcinoma progression via enhancing angiogenesis

C Wei, J Chen, Q Yu, Y Qin, T Huang… - PLOS Neglected …, 2024 - journals.plos.org
Background Clonorchis sinensis (C. sinensis) infection plays an important role in the
progression of hepatocarcinogenesis. However, its specific role in HCC progression …

Exploring the effects of 4-chloro-o-phenylenediamine on human fibrinogen: A comprehensive investigation via biochemical, biophysical and computational …

Y Singh, R Ahmad, A Raza, MS Warsi… - International Journal of …, 2024 - Elsevier
Fibrinogen (Fg), an essential plasma glycoprotein involved in the coagulation cascade,
undergoes structural alterations upon exposure to various chemicals, impacting its …

Body mass index and fat influences the role of Bifidobacterium genus in lupus patients concerning fibrinogen levels

L Chero-Sandoval, A Higuera-Gómez… - Frontiers in …, 2024 - frontiersin.org
Introduction Metabolic disorders and autoimmune diseases elicit distinct yet interconnected
manifestations of inflammation, which may be boosted by an excess of body adiposity. The …

The Promising Role of Selenium and Yeast in the Fight Against Protein Amyloidosis

M Kieliszek, K Sapazhenkava - Biological Trace Element Research, 2024 - Springer
In recent years, increasing attention has been paid to research on diseases related to the
deposition of misfolded proteins (amyloids) in various organs. Moreover, modern scientists …