Integrons are versatile gene acquisition systems commonly found in bacterial genomes.
They are ancient elements that are a hot spot for genomic complexity, generating phenotypic …

Integrons are assembly platforms—DNA elements that acquire open reading frames
embedded in exogenous gene cassettes and convert them to functional genes by ensuring …

Integrons recombine gene arrays and favor the spread of antibiotic resistance. Their broader
roles in bacterial adaptation remain mysterious, partly due to lack of computational tools. We …

Integrons are genetic elements able to acquire and rearrange open reading frames (ORFs)
embedded in gene cassette units and convert them to functional genes by ensuring their …

Gene cassettes are small mobile elements, consisting of little more than a single gene and
recombination site, which are captured by larger elements called integrons. Several …

Sepsis is a major health problem. The concept that sepsis mortality is the result of an
uncontrolled hyperinflammatory host response has recently been challenged. It is now …

The integron is a powerful system which, by capturing, stockpiling, and rearranging new
functions carried by gene encoding cassettes, confers upon bacteria a rapid adaptation …

Integrons facilitate the capture of potentially adaptive exogenous genetic material by their
host genomes. It is now clear that integrons are not limited to the clinical contexts in which …

Integrons were first identified because of their central role in assembling and disseminating
antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically …

Structured forms of DNA with intrastrand pairing are generated in several cellular processes
and are involved in biological functions. These structures may arise on single-stranded DNA …