Injured peripheral nerves regenerate their lost axons but functional recovery in humans is
frequently disappointing. This is so particularly when injuries require regeneration over long …

Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Aging deeply influences several morphologic and functional features of the peripheral
nervous system (PNS). Morphologic studies have reported a loss of myelinated and …

Skeletal Muscle: Form and Function, Second Edition, provides readers with a detailed
understanding of the different facets of muscle physiology. Meticulously researched and …

Diabetic neuropathy is the most common peripheral neuropathy in western countries.
Although every effort has been made to clarify the pathogenic mechanism of diabetic …

Injuries to peripheral nerves can cause paralysis and sensory disturbances, but such
functional impairments are often short lived because of efficient regeneration of damaged …

Severe peripheral nerve injuries often result in permanent loss of function of the affected
limb. Current treatments are limited by their efficacy in supporting nerve regeneration and …

Injuries to peripheral nerves still represent one of the most challenging surgical problems.
Severance of major nerve trunks in the upper extremity causes total or subtotal loss of …

A century ago, Ramon y Cajal described the generalized response of regenerating
peripheral axons to their environment. By using mice that express fluorescent proteins in …

Alzheimer's disease is associated with a specific pattern of pathological changes in the brain
that result in neurodegeneration and the progressive development of dementia. Pathological …