Kaposi sarcoma herpesvirus pathogenesis
G Mariggio, S Koch, TF Schulz - … Transactions of the …, 2017 - royalsocietypublishing.org
Kaposi sarcoma herpesvirus (KSHV), taxonomical name human gammaherpesvirus 8, is a
phylogenetically old human virus that co-evolved with human populations, but is now only …
phylogenetically old human virus that co-evolved with human populations, but is now only …
Kaposi Sarcoma-associated Herpesvirus: mechanisms of oncogenesis
TF Schulz, E Cesarman - Current opinion in virology, 2015 - Elsevier
Highlights•KSHV/HHV8 causes three human diseases: Kaposi Sarcoma, Primary Effusion
Lymphoma and the plasma cell variant of Multicentric Castleman Disease.•These occur …
Lymphoma and the plasma cell variant of Multicentric Castleman Disease.•These occur …
Modulation of the cGAS-STING DNA sensing pathway by gammaherpesviruses
Z Ma, SR Jacobs, JA West, C Stopford… - Proceedings of the …, 2015 - National Acad Sciences
Infection of cells with DNA viruses triggers innate immune responses mediated by DNA
sensors. cGMP-AMP synthase (cGAS) is a key DNA sensor that produces the cyclic …
sensors. cGMP-AMP synthase (cGAS) is a key DNA sensor that produces the cyclic …
Activation of NIX-mediated mitophagy by an interferon regulatory factor homologue of human herpesvirus
Viral control of mitochondrial quality and content has emerged as an important mechanism
for counteracting the host response to virus infection. Despite the knowledge of this crucial …
for counteracting the host response to virus infection. Despite the knowledge of this crucial …
Epstein–Barr virus miR-BART20-5p regulates cell proliferation and apoptosis by targeting BAD
H Kim, H Choi, SK Lee - Cancer letters, 2015 - Elsevier
Abstract Although Epstein–Barr virus (EBV) Bam HI A rightward transcript (BART)
microRNAs (miRNAs) are ubiquitously expressed in EBV-associated tumors, the role of most …
microRNAs (miRNAs) are ubiquitously expressed in EBV-associated tumors, the role of most …
Autophagy-competent mitochondrial translation elongation factor TUFM inhibits caspase-8-mediated apoptosis
Mitochondria support multiple cell functions, but an accumulation of dysfunctional or
excessive mitochondria is detrimental to cells. We previously demonstrated that a defect in …
excessive mitochondria is detrimental to cells. We previously demonstrated that a defect in …
Direct and biologically significant interactions of human herpesvirus 8 interferon regulatory factor 1 with STAT3 and Janus kinase TYK2
Z Yang, Q Xiang, J Nicholas - PLoS pathogens, 2023 - journals.plos.org
Human herpesvirus 8 (HHV-8) encodes four viral interferon regulatory factors (vIRFs) that
target cellular IRFs and/or other innate-immune and stress signaling regulators and …
target cellular IRFs and/or other innate-immune and stress signaling regulators and …
HTLV-1 tax stabilizes MCL-1 via TRAF6-dependent K63-linked polyubiquitination to promote cell survival and transformation
The human T-cell leukemia virus type 1 (HTLV-1) Tax protein hijacks the host ubiquitin
machinery to activate IκB kinases (IKKs) and NF-κB and promote cell survival; however, the …
machinery to activate IκB kinases (IKKs) and NF-κB and promote cell survival; however, the …
Distinct roles of Kaposi's sarcoma-associated herpesvirus-encoded viral interferon regulatory factors in inflammatory response and cancer
P Baresova, PM Pitha, B Lubyova - Journal of Virology, 2013 - Am Soc Microbiol
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiologic agent associated with
Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman …
Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and multicentric Castleman …
STAT and Janus kinase targeting by human herpesvirus 8 interferon regulatory factor in the suppression of type-I interferon signaling
Q Xiang, Z Yang, J Nicholas - PLoS pathogens, 2022 - journals.plos.org
Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma (KS)-associated
herpesvirus, is involved etiologically in AIDS-associated KS, primary effusion lymphoma …
herpesvirus, is involved etiologically in AIDS-associated KS, primary effusion lymphoma …