The systemic immune response to trauma: an overview of pathophysiology and treatment

JM Lord, MJ Midwinter, YF Chen, A Belli, K Brohi… - The Lancet, 2014 - thelancet.com
Improvements in the control of haemorrhage after trauma have resulted in the survival of
many people who would otherwise have died from the initial loss of blood. However, the …

Immunosenescence, inflammaging, and frailty: role of myeloid cells in age-related diseases

A Bleve, F Motta, B Durante, C Pandolfo… - Clinical reviews in …, 2022 - Springer
The immune system is the central regulator of tissue homeostasis, ensuring tissue
regeneration and protection against both pathogens and the neoformation of cancer cells. Its …

Cortisol and DHEA in development and psychopathology

HS Kamin, DA Kertes - Hormones and behavior, 2017 - Elsevier
Dehydroepiandrosterone (DHEA) and cortisol are the most abundant hormones of the
human fetal and adult adrenals released as end products of a tightly coordinated endocrine …

Understanding how we age: insights into inflammaging

D Baylis, DB Bartlett, HP Patel, HC Roberts - Longevity & healthspan, 2013 - Springer
Inflammaging is characterized by the upregulation of the inflammatory response that occurs
with advancing age; its roots are strongly embedded in evolutionary theory. Inflammaging is …

Aging of the innate immune system

AC Shaw, S Joshi, H Greenwood, A Panda… - Current opinion in …, 2010 - Elsevier
The innate immune system is composed of a network of cells including neutrophils, NK and
NKT cells, monocytes/macrophages, and dendritic cells that mediate the earliest interactions …

Immunosenescence: emerging challenges for an ageing population

D Aw, AB Silva, DB Palmer - Immunology, 2007 - Wiley Online Library
It is now becoming apparent that the immune system undergoes age‐associated alterations,
which accumulate to produce a progressive deterioration in the ability to respond to …

Does singing facilitate social bonding?

G Kreutz - Music and Medicine, 2014 - mmd.iammonline.com
Psychobiological effects of amateur choral singing were studied in a naturalistic controlled
within-subjects trial. A mixed group of novice and experienced singers (N= 21) filled out brief …

Aging, inflammation and cancer

B Bottazzi, E Riboli, A Mantovani - Seminars in immunology, 2018 - Elsevier
Aging is a key aspect of neoplasia at the level of cells, individuals and populations.
Unrestrained expression and production of inflammatory mediators is a key feature of aging …

Dehydroepiandrosterone (DHEA)—a precursor steroid or an active hormone in human physiology (CME)

AM Traish, HP Kang, F Saad… - The journal of sexual …, 2011 - academic.oup.com
Introduction The circulation of large amounts of dehydroepiandrosterone (DHEA) and its
sulfated derivative (DHEA‐S) suggests a physiological role in human physiology. In the …

Stress, ageing and their influence on functional, cellular and molecular aspects of the immune system

A Vitlic, JM Lord, AC Phillips - Age, 2014 - Springer
The immune response is essential for keeping an organism healthy and for defending it from
different types of pathogens. It is a complex system that consists of a large number of …