Obesity I: Overview and molecular and biochemical mechanisms

RH Lustig, D Collier, C Kassotis, TA Roepke… - Biochemical …, 2022 - Elsevier
Obesity is a chronic, relapsing condition characterized by excess body fat. Its prevalence
has increased globally since the 1970s, and the number of obese and overweight people is …

An insight into brown/beige adipose tissue whitening, a metabolic complication of obesity with the multifactorial origin

K Ziqubu, PV Dludla, SXH Mthembu… - Frontiers in …, 2023 - frontiersin.org
Brown adipose tissue (BAT), a thermoregulatory organ known to promote energy
expenditure, has been extensively studied as a potential avenue to combat obesity …

Recent advances of exosomes in soft tissue injuries in sports medicine: A critical review on biological and biomaterial applications

Y Xue, N Riva, L Zhao, J Shieh, YT Chin, A Gatt… - Journal of Controlled …, 2023 - Elsevier
Sports medicine is generally associated with soft tissue injuries including muscle injuries,
meniscus and ligament injuries, tendon ruptures, tendinopathy, rotator cuff tears, and tendon …

Mitochondrial RNA stimulates beige adipocyte development in young mice

AC Hoang, L Sasi-Szabó, T Pál, T Szabó… - Nature …, 2022 - nature.com
Childhood obesity is a serious public health crisis and a critical factor that determines future
obesity prevalence. Signals affecting adipocyte development in early postnatal life have a …

Browning epicardial adipose tissue: friend or foe?

E Doukbi, A Soghomonian, C Sengenès, S Ahmed… - Cells, 2022 - mdpi.com
The epicardial adipose tissue (EAT) is the visceral fat depot of the heart which is highly
plastic and in direct contact with myocardium and coronary arteries. Because of its singular …

Bioactive dietary components—Anti‐obesity effects related to energy metabolism and inflammation

C Bertoncini‐Silva, JM Zingg, PG Fassini… - BioFactors, 2023 - Wiley Online Library
Obesity is the result of the long‐term energy imbalance between the excess calories
consumed and the few calories expended. Reducing the intake of energy dense foods (fats …

Role of the endocannabinoid system in the adipose tissue with focus on energy metabolism

V Rakotoarivelo, J Sihag, N Flamand - Cells, 2021 - mdpi.com
The endocannabinoid system is involved in a wide range of processes including the control
of energy acquisition and expenditure. Endocannabinoids and their receptors are present in …

Aquaporins: New players in breast cancer progression and treatment response

V Charlestin, D Fulkerson, CE Arias Matus… - Frontiers in …, 2022 - frontiersin.org
Aquaporins (AQPs) are a family of small transmembrane proteins that selectively transport
water and other small molecules and ions following an osmotic gradient across cell plasma …

Muscle-derived beige adipose precursors secrete promyogenic exosomes that treat rotator cuff muscle degeneration in mice and are identified in humans by single …

MR Davies, S Garcia, M Liu, H Chi… - … American Journal of …, 2022 - journals.sagepub.com
Background: Muscle atrophy, fibrosis, and fatty infiltration are common to a variety of sports-
related and degenerative conditions and are thought to be irreversible. Fibroadipogenic …

The impact of adipokines on vascular networks in adipose tissue

M Vliora, C Ravelli, E Grillo, M Corsini… - Cytokine & Growth …, 2023 - Elsevier
Adipose tissue (AT) is a highly active and plastic endocrine organ. It secretes numerous
soluble molecules known as adipokines, which act locally to AT control the remodel and …