The structure and function of biomolecules are strongly influenced by their hydration shells.
Structural fluctuations and molecular excitations of hydrating water molecules cover a broad …

When Szent-Györgyi called water the “matrix of life”, 1 he was echoing an old sentiment.
Paracelsus in the 16th century said that “water was the matrix of the world and of all its …

Solvation of molecules in water is at the heart of a myriad of molecular phenomena and of
crucial importance to understanding such diverse issues as chemical reactivity or …

One of the fundamental challenges of physical biology is to understand the relationship
between protein dynamics and function. At physiological temperatures, functional motions …

Hydration water is the natural matrix of biological macromolecules and is essential for their
activity in cells. The coupling between water and protein dynamics has been intensively …

Protein hydration shell dynamics play an important role in biochemical processes including
protein folding, enzyme function, and molecular recognition. We present here a comparison …

Scattering techniques, in particular electron, neutron and X-ray scattering have played a
major role in elucidating the static and dynamic structure of biologically relevant …

Hydration shell dynamics plays a critical role in protein folding and biochemical activity and
has thus been actively studied through a broad range of techniques. While all observations …

There is considerable evidence for the slaving of biomolecular dynamics to the motions of
the surrounding solvent environment, but to date there have been few direct experimental …

Surface and internal water dynamics of molecules and soft matter are of great relevance to
their structure and function, yet the experimental determination under ambient and steady …