Nutrition and immunity: lessons for COVID-19

PC Calder - Nutrition & Diabetes, 2021 - nature.com
The role of the immune system is to protect the individual against pathogenic organisms.
Nutrition is one of multiple factors that determines the immune response and good nutrition …

The relevance of a physical active lifestyle and physical fitness on immune defense: mitigating disease burden, with focus on COVID-19 consequences

TO Filgueira, A Castoldi, LER Santos… - Frontiers in …, 2021 - frontiersin.org
The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is a fast spreading
virus leading to the development of Coronavirus Disease-2019 (COVID-19). Severe and …

Beyond chronological age: frailty and multimorbidity predict in-hospital mortality in patients with coronavirus disease 2019

A Marengoni, A Zucchelli, DL Vetrano… - The Journals of …, 2021 - academic.oup.com
Background We evaluated whether frailty and multimorbidity predict in-hospital mortality in
patients with COVID-19 beyond chronological age. Method A total of 165 patients admitted …

Association of frailty with outcomes in individuals with COVID‐19: a living review and meta‐analysis

F Dumitrascu, KE Branje, ES Hladkowicz… - Journal of the …, 2021 - Wiley Online Library
Abstract Background and Objectives Frailty leaves older adults vulnerable to adverse health
outcomes. Frailty assessment is recommended by multiple COVID‐19 guidelines to inform …

Probable delirium is a presenting symptom of COVID-19 in frail, older adults: a cohort study of 322 hospitalised and 535 community-based older adults

MB Zazzara, RS Penfold, AL Roberts, KA Lee… - Age and …, 2021 - academic.oup.com
Background Frailty, increased vulnerability to physiological stressors, is associated with
adverse outcomes. COVID-19 exhibits a more severe disease course in older, comorbid …

The role of frailty on adverse outcomes among older patients with COVID-19

H Kundi, EHÖ Çetin, U Canpolat, S Aras, O Celik… - Journal of Infection, 2020 - Elsevier
Background Diagnosis and screening of frailty, a condition characterized by an increased
vulnerability to adverse outcomes of COVID-19, has emerged as an essential clinical tool …

Consequences of the COVID-19 pandemic on admissions to general hospital psychiatric wards in Italy: reduced psychiatric hospitalizations and increased suicidality

T Boldrini, P Girardi, M Clerici, A Conca, C Creati… - Progress in Neuro …, 2021 - Elsevier
Aims The present investigation aimed at evaluating differences in psychiatric
hospitalizations in Italy during and after the lockdown due to the novel coronavirus disease …

Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank

F Petermann-Rocha, P Hanlon, SR Gray, P Welsh… - BMC medicine, 2020 - Springer
Background Frailty has been associated with worse prognosis following COVID-19 infection.
While several studies have reported the association between frailty and COVID-19 mortality …

Underlying vulnerabilities to the cytokine storm and adverse COVID-19 outcomes in the aging immune system

LS Nidadavolu, JD Walston - The Journals of Gerontology …, 2021 - academic.oup.com
Older adults are far more vulnerable to adverse health outcomes and mortality after
contracting COVID-19. There are likely multiple age-related biological, clinical, and …

COVID-19 vaccines: current and future perspectives

L Soraci, F Lattanzio, G Soraci, ME Gambuzza… - Vaccines, 2022 - mdpi.com
Currently available vaccines against severe acute respiratory syndrome coronavirus-2
(SARS-CoV-2) are highly effective but not able to keep the coronavirus disease 2019 …