Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

Recent studies applying advanced imaging techniques are changing the way we
understand bacterial cell surfaces, bringing new knowledge on everything from single-cell …

Genetically identical bacterial cells commonly display different phenotypes. This phenotypic
heterogeneity is well known for stress responses, where it is often explained as bet hedging …

The rise of antibiotic resistance is a threat to global health. Rapid and comprehensive
analysis of infectious strains is critical to reducing the global use of antibiotics, as informed …

The interactions between bacteria and bacteriophage have important roles in the global
ecosystem; in turn changes in environmental parameters affect the interactions between …

Antibiotics effective against Gram‐negative ESKAPE pathogens are a critical area of unmet
need. Infections caused by these pathogens are not only difficult to treat but finding new …

One of the deepest branches in the tree of life separates the Archaea from the Bacteria.
These prokaryotic groups have distinct cellular systems including fundamentally different …

Antimicrobial resistance is an urgent threat to human health, and new antibacterial drugs are
desperately needed, as are research tools to aid in their discovery and development …

Gram-negative bacteria are intrinsically resistant to many antibiotics, due in large part to the
permeability barrier formed by their cell envelope. The complex and synergistic interplay of …

The interaction between a cell and its environment shapes fundamental intracellular
processes such as cellular metabolism. In most cases growth rate is treated as a proximal …