Clefts of the lip and palate are generally divided into two groups, isolated cleft palate and
cleft lip with or without cleft palate, representing a heterogeneous group of disorders …

The epithelial and mesenchymal cells involved in early embryonic facial development are
guided by complex regulatory mechanisms. Any factor perturbing the growth, approach and …

Compared with the embryonic development of other organs, development of the secondary
palate is seemingly simple. However, each step of palatogenesis, from initiation until …

Orofacial clefts are the most common craniofacial birth defects and one of the most common
congenital malformations in humans. They require complex multidisciplinary treatment and …

Tissue and molecular heterogeneities are present in the developing secondary palate along
the anteroposterior (AP) axis in mice. Here, we show that Wnt5a and its receptor Ror2 are …

Orofacial clefts are common birth defects of multifactorial etiology. Several novel approaches
have recently been applied to investigate the causes of clefts. These include examining …

White adipose tissue (WAT) mass is determined by adipocyte size and number. While
adipocytes are continuously turned over, the mechanisms controlling fat cell number in WAT …

During mammalian development, a pair of shelves fuses to form the secondary palate, a
process that requires the adhesion of the medial edge epithelial tissue (MEE) of each shelf …

Clefts of the palate are common birth defects requiring extensive treatment. They appear to
be caused by multiple genetic and environmental factors during palatogenesis. This may …

Pierre Robin sequence (PRS) is a craniofacial anomaly comprising mandibular hypoplasia,
cleft secondary palate and glossoptosis leading to life‐threatening obstructive apnea and …