Metals and molecular carcinogenesis

Y Zhu, M Costa - Carcinogenesis, 2020 - academic.oup.com
Many metals are essential for living organisms, but at higher doses they may be toxic and
carcinogenic. Metal exposure occurs mainly in occupational settings and environmental …

[HTML][HTML] Zinc finger structure determination by NMR: Why zinc fingers can be a handful

D Neuhaus - Progress in nuclear magnetic resonance spectroscopy, 2022 - Elsevier
Zinc fingers can be loosely defined as protein domains containing one or more tetrahedrally-
co-ordinated zinc ions whose role is to stabilise the structure rather than to be involved in …

Introduced oxygen vacancies in cadmium ferrite anode materials via Zn2+ incorporation for high performance lithium-ion batteries

MMS Sanad, AA Azab, TA Taha - Materials Science in Semiconductor …, 2022 - Elsevier
Cationic substitution strategy was recognized as an effective approach to create a defective
structure and increase the oxygen vacancies in the crystal structure for improving the …

[HTML][HTML] Structural zinc binding sites shaped for greater works: Structure-function relations in classical zinc finger, hook and clasp domains

M Padjasek, A Kocyła, K Kluska, O Kerber… - Journal of Inorganic …, 2020 - Elsevier
Metal ions are essential elements present in biological systems able to facilitate many
cellular processes including proliferation, signaling, DNA synthesis and repair. Zinc ion (Zn …

Heavy metal ions exchange driven protein phosphorylation cascade functions in genomic instability in spermatocytes and male infertility

RY Li, D Yang, YJ He, Y Zhou, CC Li, LB Li… - Nucleic Acids …, 2023 - academic.oup.com
DNA double-strand breaks (DSBs) are functionally linked to genomic instability in
spermatocytes and to male infertility. The heavy metal cadmium (Cd) is known to induce …

[HTML][HTML] Cadmium effects on superoxide dismutase 1 in human cells revealed by NMR

P Polykretis, F Cencetti, C Donati, E Luchinat, L Banci - Redox biology, 2019 - Elsevier
Cadmium is a toxic pollutant that in recent decades has become more widespread in the
environment due to anthropogenic activities, significantly increasing the risk of exposure …

The prokaryotic zinc‐finger: structure, function and comparison with the eukaryotic counterpart

G Malgieri, M Palmieri, L Russo, R Fattorusso… - The FEBS …, 2015 - Wiley Online Library
Classical zinc finger (ZF) domains were thought to be confined to the eukaryotic kingdom
until the transcriptional regulator Ros protein was identified in Agrobacterium tumefaciens …

[HTML][HTML] Characterization of early transcriptional responses to cadmium in the root and leaf of Cd-resistant Salix matsudana Koidz

J Yang, K Li, W Zheng, H Zhang, X Cao, Y Lan, C Yang… - BMC genomics, 2015 - Springer
Abstract Background Salix matsudana Koidz. is a fast growing tree species. It has a high
cadmium (Cd) tolerance capacity, making it potentially suitable for phytoremediation …

Structural metal sites in nonclassical zinc finger proteins involved in transcriptional and translational regulation

SJ Lee, SLJ Michel - Accounts of Chemical Research, 2014 - ACS Publications
Conspectus Zinc finger (ZF) proteins are a large family of metalloproteins that utilize zinc for
structural purposes. Zinc coordinates to a combination of cysteine thiol and histidine …

The molecular basis of Acinetobacter baumannii cadmium toxicity and resistance

SF Alquethamy, FG Adams, R Maharjan… - Applied and …, 2021 - Am Soc Microbiol
Acinetobacter species are ubiquitous Gram-negative bacteria that can be found in water, in
soil, and as commensals of the human skin. The successful inhabitation of Acinetobacter …