The neuromuscular junction is the chemical synapse between motor neurons and skeletal
muscle fibers. It is designed to reliably convert the action potential from the presynaptic …

During the development of peripheral nerves, neural crest cells generate myelinating and
non-myelinating glial cells in a process that parallels gliogenesis from the germinal layers of …

▪ Abstract We describe the formation, maturation, elimination, maintenance, and
regeneration of vertebrate neuromuscular junctions (NMJs), the best studied of all synapses …

Functional recovery from peripheral nerve injury and repair depends on a multitude of
factors, both intrinsic and extrinsic to neurons. Neuronal survival after axotomy is a …

Schizophrenia is a highly debilitating mental disorder that affects∼ 1% of the general
population, yet it continues to be poorly understood. Recent studies have identified …

Publisher Summary This chapter focuses on neuregulins (NRGs) that are the signaling
proteins that mediate cell–cell interactions in the nervous system, heart, breast, and other …

Synapses, as fundamental units of the neural circuitry, enable complex behaviors. The
neuromuscular junction (NMJ) is a synapse type that forms between motoneurons and …

The role of neurotrophic factors in the maintenance and survival of peripheral neuronal cells
has been the subject of numerous studies. Administration of exogenous neurotrophic factors …

The neuromuscular junction (NMJ) is a highly reliable synapse to carry the control of the
motor commands of the nervous system over the muscles. Its development, organization …

Spinal muscular atrophy (SMA) is a common pediatric neuromuscular disorder caused by
insufficient levels of the survival of motor neuron (SMN) protein. Studies involving SMA …