The late 1990s were banner years in molecular neuroscience; seminal studies
demonstrated that local protein synthesis, at or near synapses, was necessary for synaptic …

Post-traumatic stress disorder (PTSD) is a stress-associated complex and debilitating
psychiatric disorder due to an imbalance of neurotransmitters in response to traumatic …

Chronic traumatic stress results in various psychiatric disorders, especially posttraumatic
stress disorder (PTSD). Previous study demonstrated that curculigoside (CUR) a component …

Humans are ubiquitously exposed to endocrine disrupting chemicals (EDCs), substances
that interfere with endogenous hormonal signaling. Exposure during early development is of …

Background Schizophrenia (SCZ) is caused by an interplay of polygenic risk and
environmental factors, which may alter regulators of gene expression leading to pathogenic …

Mammalian oocyte development depends on the temporally controlled translation of
maternal transcripts, particularly in the coordination of meiotic and early embryonic …

A self-cleaving ribozyme that maps to an intron of the cytoplasmic polyadenylation element-
binding protein 3 (Cpeb3) gene is thought to play a role in human episodic memory, but the …

Both the brain-derived neurotrophic factor (BDNF) and glucocorticoids (GCs) play multiple
roles in various aspects of neurons, including cell survival and synaptic function. BDNF and …

Background Local translation at synapses is important for rapidly remodeling the synaptic
proteome to sustain long-term plasticity and memory. While the regulatory mechanisms …

Glioblastoma multiforme (GBM) is the most aggressive primary malignant brain tumor in
adults, with a poor prognosis that highlights a dire clinical need for innovative therapeutic …