Introduction: Acridine derivatives have been extensively explored as potential therapeutic
agents for the treatment of a number of diseases, such as cancer, Alzheimer's, and bacterial …

Background: The acridine scaffold is of interest since its DNA affinity and intercalative
properties make it an important pharmacophore for the design of antitumor drugs targeting …

A total of 21 novel xanthone and acridone derivatives were synthesized using the reactions
of 1, 2, 4-triazine derivatives with 1-hydroxy-3-methoxy-10-methylacridone, 1, 3-dimethoxy …

The synthesis of imidazo[1,5- a ]quinolines via a decarboxylative cyclization under metal-free
conditions - RSC Advances (RSC Publishing) DOI:10.1039/C8RA03786H Royal Society of …

Unsymmetrical bisacridines (UAs) represent a novel class of anticancer agents previously
synthesized by our group. Our recent studies have demonstrated their high antitumor …

New unsymmetrical bisacridines (UAs) demonstrated high activity not only against a set of
tumor cell lines but also against human tumor xenografts in nude mice. Representative UA …

Introduction: Acridines are highly important heterocyclic compounds with immense
biological significance as they act as the central core of antitumor, anti-protozoan, antiviral …

The metabolism of antitumor-active 5-diethylaminoethylamino-8-hydroxyimidazoacridinone
(C-1311) has been investigated widely over the last decade but some aspects of molecular …

5-Diethylaminoethylamino-8-hydroxyimidazoacridinone (C-1311) is an antitumor agent that
is also active against autoimmune diseases. The intention of the present studies was to …

Biological as well as other important aspects of acridine have been studied and reviewed by
number of prominent researchers so far. But interestingly, from the 2000s, acridones, the …