Long version on the S3 guidelines for axial spondyloarthritis including Bechterew's disease and early forms, Update 2019: Evidence-based guidelines of the German …

U Kiltz, J Braun, DGRh, A Becker, DEGAM… - Zeitschrift für …, 2019 - Springer
Spondyloarthritiden (SpA) sind entzündlich rheumatische Erkrankungen, die durch
Entzündungen im Bereich der Wirbelsäule gekennzeichnet sind, welche häufig zu …

Comparison of biologics and small-molecule drugs in axial spondyloarthritis: a systematic review and network meta-analysis

E Zhou, J Wu, K Zeng, M Wang, Y Yin - Frontiers in Pharmacology, 2023 - frontiersin.org
Background: Biologics and small-molecule drugs have become increasingly accepted
worldwide in the treatment of axial spondyloarthritis (axSpA), including ankylosing …

Comparative efficacy and safety of secukinumab and adalimumab in patients with active ankylosing spondylitis: a Bayesian network meta-analysis of randomized …

YH Lee, GG Song - Journal of Rheumatic Diseases, 2017 - synapse.koreamed.org
Objective This study assessed the efficacy and safety of secukinumab and adalimumab in
patients with active ankylosing spondylitis (AS). Methods A Bayesian network meta-analysis …

Clinical and economic benefit of advanced therapies for the treatment of active ankylosing spondylitis

JA Walsh, CD Saffore, EB Collins, A Ostor - Rheumatology and Therapy, 2023 - Springer
Introduction Recent changes to treatment guidelines for ankylosing spondylitis (AS) have
listed first-line advanced therapies as tumor necrosis factor (TNF), interleukin (IL)-17, and …

Metabolic syndrome in patients with ankylosing spondylitis receiving anti-TNFα therapy: association with predictors of cardiovascular risk

DG Maia, KL Augusto, MC Bezerra… - Clinical rheumatology, 2017 - Springer
The purposes of this study were to determine the prevalence of metabolic syndrome (MetS)
in patients with ankylosing spondylitis (AS) receiving anti-TNFα therapy and evaluate the …

Esculetin induces apoptosis of SMMC-7721 cells through IGF-1/PI3K/Akt-mediated mitochondrial pathways

J Li, S Li, X Wang, H Wang - Canadian Journal of Physiology …, 2017 - cdnsciencepub.com
Esculetin (6, 7-dihydroxycoumarin) is a coumarin derivative extracted from natural plants
and has been reported to have anticancer activity. However, the mechanism by which …

Budget impact analysis of secukinumab versus adalimumab in the treatment of ankylosing spondylitis

T Purmonen, S Törmälehto, H Wahlman… - Journal of medical …, 2019 - Taylor & Francis
Background: Biologic treatments have enhanced the treatment outcomes of patients with
active ankylosing spondylitis (AS). Until recently, TNF-alpha-inhibitors have been the only …

A cost per responder analysis of secukinumab vs adalimumab for the treatment of ankylosing spondylitis from the Korean perspective

D Kim, H Kim, SH Cho, MC Park - International Journal of …, 2019 - Wiley Online Library
Aim To compare the cost‐effectiveness of secukinumab vs adalimumab at 1 and 2 years of
treatment in patients with ankylosing spondylitis (AS) by analyzing the cost per responder …

Mirror, mirror, on the wall, which is the most effective biologic of all?

A Deodhar - The Journal of Rheumatology, 2018 - jrheum.org
We all consider the “comparative effectiveness” of available treatment options in daily
clinical practice, knowingly or unknowingly. In fact, that and “comparative safety” are 2 of our …

[HTML][HTML] Cost-effectiveness study of treatment with biologic disease-modifying antirheumatic drugs in adult patients with active ankylosing spondylitis

RO Dreval - Modern Rheumatology Journal, 2021 - mrj.ima-press.net
Objective: to conduct a cost-effectiveness study of major biologic disease-modifying
antirheumatic drugs (bDMARDs) used for the treatment of ankylosing spondylitis (AS) in …