METHODS Comprehensive searches based on the concepts of “AI” and “urothelial cancer”
were conducted in MEDLINE, EMBASE, Web of Science, and Scopus. Study selection and …

Simple Summary Liver cancer is one of the most common cancers; however, the molecular
mechanisms of liver tumorigenesis and progression are not completely understood. In the …

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by
the progressive degeneration of motor neurons, leading to muscle atrophy, paralysis and …

Pathway analysis, including nontopology-based (non-TB) and topology-based (TB)
methods, is widely used to interpret the biological phenomena underlying differences in …

Bladder cancer is a common malignancy with mechanisms of pathogenesis and
progression. This study aimed to identify the prognostic hub genes, which are the central …

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic respiratory disease
characterized by peripheral distribution of bilateral pulmonary fibrosis that is more …

Individual gene expression and molecular pathway activation profiles were shown to be
effective biomarkers in many cancers. Here, we used the human interactome model to …

BACKGROUND Cholangiocarcinoma (CCA) is a lethal malignancy with limited treatment
options and poor prognosis. The PEA3 subfamily of E26 transformation specific genes …

Bladder urothelial carcinoma (BLCA) is a common malignant tumor of the human urinary
system, and a large proportion of BLCA patients have a poor prognosis. Therefore, there is …

Background: Previous studies have suggested that patients with lung adenocarcinoma
(LUAD) will significantly benefit from epidermal growth factor receptor tyrosine kinase …