Intracerebral hemorrhage (ICH) is a devastating clinical event without effective therapies.
Increasing evidence suggests that inflammatory mechanisms are involved in the …

Free radical production is increased in ischemic and hemorrhagic stroke, leading to
oxidative stress that contributes to brain damage. The measurement of oxidative stress in …

The clinical usefulness of brain machine interfaces that employ penetrating silicon
microelectrode arrays is limited by inconsistent performance at chronic time points. While it …

Object. Matrix metalloproteinases (MMPs) are overexpressed in the presence of some
neurological diseases in which blood—brain barrier disruption exists. The authors …

✓ Primary intracerebral hemorrhage (ICH) is associated with a high mortality rate and
severe morbidity. The treatment of choice is still controversial, given that data from several …

Peroxisome proliferator-activated receptor-γ (PPARγ) is a transcription factor that regulates
the expression of various gene products that are essential in lipid and glucose metabolism …

Background and Purpose—Extravasation of blood is associated with intracerebral
hemorrhage and head trauma. The mechanism of brain cell injury associated with …

Subarachnoid hemorrhage (SAH) is a devastating subtype of stroke. Microglial macrophage-
inducible C-type lectin (Mincle) receptor launches microglial innate immunity after SAH, and …

Object. Adenovirus-mediated overexpression of interleukin-1 receptor antagonist (IL-1ra)
attenuates the inflammatory reaction and brain injury that follows focal cerebral ischemia …

Background Subarachnoid haemorrhage (SAH) elicits rapid pathological changes in the
structure and function of parenchymal vessels (≤ 100 μm). The role of neutrophils in these …