Traditional approaches to prevention of the complications of type 2 diabetes (T2D) and
obesity have focused on reduction of blood glucose and body weight. The development of …

Abstract Sodium-glucose co-transporter-2 (SGLT2) inhibitors offer significant outcome
benefits beyond glucose lowering, including reduced risk of cardiovascular death, all-cause …

Type 2 diabetes mellitus (T2DM) is a risk factor for osteoporosis. The effects of T2DM and
anti-diabetic agents on bone and mineral metabolism have been observed. Sodium …

Abstract Sodium‐glucose cotransporter 2 (SGLT2) inhibitors, originally designed to manage
blood sugar levels in individuals with type 2 diabetes (T2D), have emerged as a crucial …

In recent years, the role of sodium glucose cotransporter 2 (SGLT-2) inhibitors (SGLT2i) has
expanded beyond the treatment of diabetes alone to the prevention and treatment of heart …

Diabetes poses a significant risk to bone health, with Type 1 diabetes (T1D) having a more
detrimental impact than Type 2 diabetes (T2D). The group of hormones known as incretins …

Purpose Both heart failure and its treatment with diuretics or SGLT2 inhibitors increase fall
risk in older adults. Therefore, decisions to continue or deprescribe diuretics or SGLT2 …

Understanding patients' degree of frailty is crucial for tailoring clinical care for older adults
based on their physiologic reserve and health needs (“frailty‐guided clinical care”). Two …

Results After weighting, we identified a total of 38,994 new users of a SGLT2 inhibitor and
37,449 new users of a DPP-4 inhibitor and observed a total of 342 fractures at 180 days and …

Importance Postmenopausal individuals with type 2 diabetes are susceptible to fractures
due to the interaction of elevated blood glucose levels and a deficiency of the hormone …