Background Tauopathies are a class of neurodegenerative disorders characterized by
neuronal and/or glial tau-positive inclusions. Main body Clinically, tauopathies can present …

Background Consensus criteria for classifying tremor disorders were published by the
International Parkinson and Movement Disorder Society in 1998. Subsequent advances with …

Background: PSP is a neuropathologically defined disease entity. Clinical diagnostic criteria,
published in 1996 by the National Institute of Neurological Disorders and Stroke/Society for …

Tau pathology is the main driver of neuronal dysfunction in 4-repeat tauopathies, including
cortico-basal degeneration and progressive supranuclear palsy. Tau is assumed to spread …

To improve the specificity and sensitivity of the clinical diagnosis of progressive
supranuclear palsy (PSP, Steele-Richardson-Olszewski syndrome), the National Institute of …

Tau is a microtubule-associated protein with versatile functions in the dynamic assembly of
the neuronal cytoskeleton. Four-repeat (4R-) tauopathies are a group of neurodegenerative …

We have reviewed the clinical and pathological diagnoses of 143 cases of parkinsonism
seen by neurologists associated with the movement disorders service at The National …

The correct diagnosis of Parkinson's disease is important for prognostic and therapeutic
reasons and is essential for clinical research. Investigations of the diagnostic accuracy for …

Abstract We devised a Progressive Supranuclear Palsy (PSP) Rating Scale comprising 28
items in six categories: daily activities (by history), behaviour, bulbar, ocular motor, limb …

Background The prevalence of progressive supranuclear palsy (PSP) and multiple system
atrophy (MSA) in the general population is unknown. Clinicopathological studies of patients …