Vertebrate hemoglobin (Hb) and myoglobin (Mb) were among the first proteins whose
structures and sequences were determined over 50 years ago. In the subsequent …

There are many co-regulated genes in eukaryotic cells. The coordinated activation or
repression of such genes occurs at specific stages of differentiation, or under the influence of …

The extraordinary breath-hold diving capacity of crocodilians has been ascribed to a unique
mode of allosterically regulating hemoglobin (Hb)-oxygenation in circulating red blood cells …

The transforming growth factor-β (TGF-β) gene family is unique to animals and is involved in
various important processes including tissue regeneration. Here, we identified 52 TGF-β …

In bony vertebrates, skeletal mineralization relies on the secretory calcium-binding
phosphoproteins (Scpp) family whose members are acidic extracellular proteins …

Uncovering the genetic basis of hypoxic adaptation is one of the most active research areas
in evolutionary biology. Among air-breathing vertebrates, modifications of hemoglobin (Hb) …

Essential for calcium homeostasis, TRPV5 and TRPV6 are calcium-selective channels
belonging to the transient receptor potential (TRP) gene family. In this study, we investigated …

Hemoglobin (Hb) has been identified in at least 14 molluscan taxa so far. Research
spanning over 130 years on molluscan Hbs focuses on their genes, protein structures …

Among the numerous lineages of teleost fish that have independently transitioned from
obligate water breathing to facultative air breathing, evolved properties of hemoglobin (Hb) …

Whole-genome duplications (WGDs) are an important contributor to phenotypic innovations
in evolutionary history. The diversity of blood oxygen transport traits is the perfect reflection …