Anti-inflammatory and immunomodulatory effect of high-dose immunoglobulins in children: from approved indications to off-label use

F Conti, M Moratti, L Leonardi, A Catelli, E Bortolamedi… - Cells, 2023 - mdpi.com
Background: The large-scale utilization of immunoglobulins in patients with inborn errors of
immunity (IEIs) since 1952 prompted the discovery of their key role at high doses as …

Intravenous immunoglobulin: mechanism of action in autoimmune and inflammatory conditions

J Bayry, EA Ahmed, D Toscano-Rivero… - The Journal of Allergy …, 2023 - Elsevier
Intravenous immunoglobulin (IVIG) is the mainstay of therapy for humoral immune
deficiencies and numerous inflammatory disorders. Although the use of IVIG may be …

Early treatment of multisystem inflammatory syndrome in children

B Jonat, AS Geneslaw, CA Capone, S Shah… - …, 2023 - publications.aap.org
BACKGROUND AND OBJECTIVES Multisystem inflammatory syndrome in children (MIS-C)
is a severe hyperinflammatory illness occurring after severe acute respiratory syndrome …

Treatment of multisystem inflammatory syndrome in children

T Tong, YH Jin, M Wang, FQ Gong - World Journal of Pediatrics, 2024 - Springer
Background Multisystem inflammatory syndrome in children (MIS-C), a relatively uncommon
but severe pediatric complication, is associated with coronavirus disease 2019 (COVID-19) …

Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): a Brazilian cohort

A Cavalcanti, A Islabão, C Magalhães… - Advances in …, 2022 - SciELO Brasil
Background: Paediatric inflammatory multisystem syndrome (PIMS) associated with severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been described since mid …

New insight into the intravenous immunoglobulin treatment in Multisystem Inflammatory Syndrome in children and adults

CJ Chen, HY Kao, CH Huang, CJ Li, CH Hung… - Italian Journal of …, 2024 - Springer
Within 6 months of the coronavirus pandemic, a new disease entity associated with a
multisystem hyperinflammation syndrome as a result of a previous infection with the SARS …

Clinical profile and outcomes of multisystem inflammatory syndrome in children associated with COVID-19 virus after surgery for congenital heart defects

CS Sujana, S Wadile, CS Srinivas… - Annals of Pediatric …, 2023 - journals.lww.com
Materials and Methods: This is a prospective case–control study that included children
diagnosed to have MIS-C in the postoperative period based on clinical signs, rise in …

Update on the treatment of multisystem inflammatory syndrome in children associated with COVID-19

F Long, S Zhu, Z Wang, S Zhang, J He, X Ge… - Future Virology, 2023 - Taylor & Francis
In late 2019, SARS-CoV-2 was detected in China and spread worldwide. In rare cases,
children who were infected with COVID-19 may develop multisystem inflammatory syndrome …