Hanahan and Weinberg have proposed 10 organizing principles that enable growth and
metastatic dissemination of cancer cells. These distinctive and complementary capabilities …

The incidence and mortality of cancer have increased over the past decades. Significant
progress has been made in understanding the underpinnings of this disease and …

Cervical cancer is one of the malignant tumors with high incidence and high mortality among
women in developing countries. The main factors affecting the prognosis of cervical cancer …

Galectins are an evolutionarily ancient and widely expressed family of lectins that have
unique glycan-binding characteristics. They are pleiotropic regulators of key biological …

Galectin-7 is a soluble unglycosylated lectin that is able to bind specifically to β-
galactosides. It has been described to be involved in apoptosis, proliferation and …

Metastasis predicts poor prognosis in cancer patients. It has been recognized that specific
tumor microenvironment defines cancer cell metastasis, whereas the underlying …

There is a tremendous need for developing new useful prognostic factors in ovarian cancer.
Galectins are a family of carbohydrate binding proteins which have been suggested to serve …

Galectins are small unglycosylated soluble lectins distributed both inside and outside the
cells. They share a conserved domain for the recognition of carbohydrates (CRD). Although …

Ovarian cancer is known for its aggressive pathological features, including the capacity to
undergo epithelial to mesenchymal transition, promoting angiogenesis, metastatic potential …

Re-epithelialisation of wounded epidermis is ensured by collective cell migration of
keratinocytes. Efficient collective migration requires the maintenance of intercellular …