Central nervous system (CNS) neoplasms are difficult to treat due to their sensitive location.
Over the past two decades, the availability of patient tumor materials facilitated large scale …

The integrative use of light and nanoassemblies has made a profound impact in the
biomedical field for diagnosis, drug delivery, and phototherapy. Recent advances in the …

Bioluminescence (BL), ie, the emission of light in living organisms, has become an
indispensable tool for a plethora of applications including bioassays, biosensors, and in vivo …

Here, we establish a CT-radiomics based method for application in invasive, orthotopic
rodent brain tumour models. Twenty four NOD/SCID mice were implanted with U87R-Luc2 …

The major reason for the failure of conventional therapies is the heterogeneity and
complexity of tumor microenvironments (TMEs). Many malignant tumors reprogram their …

Simple Summary Inconsistent engraftment of luciferase-expressing tumors, especially
GL261 Red-FLuc, has been reported in the recent literature. However, techniques to …

Bioanalysis based on optical imaging has gained significant progress in the last few
decades. Luminescence probes are capable of detecting, monitoring, and tracing particular …

Bioluminescence imaging has become an essential non-invasive tool in cancer research for
monitoring various cellular processes and tumor progression in vivo. In this article, we aimed …

Animal experiments are often used to determine effects of drugs and other biological
conditions on cancer progression, but poor accuracy and reproducibility of established …

Glioblastoma (GBM) is the most aggressive brain cancer. To model GBM in research,
orthotopic brain tumor models, including syngeneic models like GL261 and genetically …