Y Gong, S Qin, L Dai, Z Tian - Signal Transduction and Targeted …, 2021 - nature.com
Abstract Coronavirus disease 2019 (COVID-19), a highly infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has infected more than …
Z Cui, P Liu, N Wang, L Wang, K Fan, Q Zhu, K Wang… - Cell, 2022 - cell.com
Summary The SARS-CoV-2 Omicron variant with increased fitness is spreading rapidly worldwide. Analysis of cryo-EM structures of the spike (S) from Omicron reveals amino acid …
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron sublineages carry distinct spike mutations resulting in escape from antibodies induced by previous infection or …
An ideal therapeutic anti-SARS-CoV-2 antibody would resist viral escape,–, have activity against diverse sarbecoviruses,,–, and be highly protective through viral neutralization,,–and …
FA Lempp, LB Soriaga, M Montiel-Ruiz, F Benigni… - Nature, 2021 - nature.com
Abstract SARS-CoV-2 infection—which involves both cell attachment and membrane fusion— relies on the angiotensin-converting enzyme 2 (ACE2) receptor, which is paradoxically …
D Pinto, MM Sauer, N Czudnochowski, JS Low… - Science, 2021 - science.org
The spillovers of betacoronaviruses in humans and the emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants highlight the need for broad …
JE Bowen, A Addetia, HV Dang, C Stewart, JT Brown… - Science, 2022 - science.org
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern comprises several sublineages, with BA. 2 and BA. 2.12. 1 having replaced the …
Analysis of the specificity and kinetics of neutralizing antibodies (nAbs) elicited by SARS- CoV-2 infection is crucial for understanding immune protection and identifying targets for …
The recent emergence of SARS-CoV-2 variants of concern,,,,,,,,–and the recurrent spillovers of coronaviruses, into the human population highlight the need for broadly neutralizing …