F Davodabadi, S Mirinejad… - Biotechnology …, 2023 - Wiley Online Library
Aptamers (Apts) are synthetic nucleic acid ligands that can be engineered to target various molecules, including amino acids, proteins, and pharmaceuticals. Through a series of …
H Song, X Chen, Y Hao, J Wang, Q Xie… - Journal of …, 2022 - Springer
Precision medicine has put forward the proposition of" precision targeting" for modern drug delivery systems. Inspired by techniques from biology, pharmaceutical sciences, and …
Metastasis is the major cause of cancer-related deaths. Invasive primary cancers often metastasize after circulating tumor cells (CTCs) enter the bloodstream or lymph node to …
H Park, G Saravanakumar, J Kim… - Advanced Healthcare …, 2021 - Wiley Online Library
The tumor microenvironment (TME), which is composed of cancer cells, stromal cells, immune cells, and extracellular matrices, plays an important role in tumor growth and …
X Wan, H Zhang, W Pan, N Li, B Tang - Chemical Communications, 2021 - pubs.rsc.org
An enzyme nanopocket based on covalent organic frameworks for long-term starvation therapy and enhanced photodynamic therapy of cancer - Chemical Communications (RSC Publishing) …
Plant virus nanoparticles (PVNPs) have inherent immune stimulatory ability, and have been investigated as immune adjuvants to stimulate an anti-tumor immune response. The …
Angiogenesis is a hallmark of cancer biology, and neoadjuvant therapies targeting either tumor vasculature or VEGF signaling have been developed to treat solid malignant tumors …
A Setia, B Vallamkonda, RR Challa, AK Mehata… - …, 2024 - ncbi.nlm.nih.gov
Modern medicine relies on a small number of key biologics, which can be found in nature but require further characterization and purification before they can be used. Since the …
EY Makhani, A Zhang, JB Haun - Nano Convergence, 2021 - Springer
Nanoparticles have drawn intense interest as delivery agents for diagnosing and treating various cancers. Much of the early success was driven by passive targeting mechanisms …