Following the discovery of HIV as a causative agent of AIDS, the expectation was to rapidly
develop a vaccine; but thirty years later, we still do not have a licensed vaccine. Progress …

One of the most exciting developments in antiviral research has been the discovery of the
direct-acting antivirals (DAAs) that effectively cure chronic hepatitis C virus (HCV) infections …

Introduction: Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are essential
components of highly active antiretroviral therapy against HIV-1 infections. Here, we provide …

Different mechanisms mediate the toxicity of RNA. Genomic retroviral mRNA hijacks infected
host cell factors to enable virus replication. The viral genomic RNA of the human …

Virus invasion activates the host's innate immune response, inducing the production of
numerous cytokines and interferons to eliminate pathogens. Except for viral DNA/RNA, viral …

The azaindole (AI) framework continues to play a significant role in the design of new
antiviral agents. Modulating the position and isosteric replacement of the nitrogen atom of AI …

SARS‐CoV‐2 has infected hundreds of millions of people with over four million dead,
resulting in one of the worst global pandemics in recent history. Neurological symptoms …

AIDS causes increasing mortality every year. With advancements in nanomedicine, different
nanomaterials (NMs) have been applied to treat AIDS and overcome its limitations. Among …

This mini review focuses on the diagnosis and treatment of virus diseases using Crisper-Cas
technology. The present paper describes various strategies involved in diagnosing diseases …

The human immunodeficiency virus (HIV) infection of the immune cells expressing the
cluster of differentiation 4 cell surface glycoprotein (CD4+ cells) causes progressive decline …