Since the introduction of the hematoxylin and eosin (H&E)-stained slide in 1876 as the
primary tool in the pathologist's toolbox up until the last decade, few tools, other than the …

Histopathology, which is the gold-standard for prostate cancer diagnosis, faces significant
challenges. With prostate cancer ranking among the most common cancers in the United …

Importance Magnetic resonance imaging (MRI) has been proposed to enhance the benefit-
to-harm ratio of prostate cancer screening, but data on repeated screening outcomes are …

Polygenic risk scores (PRSs) hold promise for disease risk assessment and prevention. The
Genomic Medicine at Veterans Affairs (GenoVA) Study is addressing three main challenges …

BACKGROUND. Precise risk stratification through MRI/ultrasound (US) fusion-guided
targeted biopsy (TBx) can guide optimal prostate cancer (PCa) management. OBJECTIVE …

Abstract Background and Objective To develop a healthcare chatbot service (AI-guided bot)
that conducts real-time conversations using large language models to provide accurate …

Background Clinical guidelines favor MRI before prostate biopsy due to proven benefits.
However, adoption patterns across the US are unclear. Methods This study used the …

Multiparametric MRI (mpMRI) of the prostate aids risk stratification of patients with elevated
PSA levels. Although most clinically significant prostate cancers are detected by mpMRI …

Diagnostic multiparametric MRI of the prostate has steadily evolved over the last three
decades and can now reliably depict the dominant tumor in most men with prostate cancer …

The utility of machine learning models in histopathology image analysis for disease
diagnosis has been extensively studied. However, efforts to stratify patient risk are relatively …