Despite abundant research in the field of antifungal drug discovery, fungal infections remain
a significant healthcare burden. There is an emerging need for the development of novel …

Infections caused by Candida albicans, often refractory and with high morbidity and
mortality, cause a heavy burden on the public health while the current antifungal drugs are …

Among the several mechanisms of multidrug resistance (MDR), overexpression of drug
efflux pumps CaCdr1p and CaMdr1p belonging to ATP binding cassette (ABC) and major …

Therapeutic deep eutectic systems (THEDES) have dramatically expanded their popularity
in the pharmaceutical field due to their ability to increase active pharmaceutical ingredients …

In recent years, fungal infections have become a serious health problem. Candida albicans
are considered as the fourth most common isolates associated with approximately 40 …

Background and Purpose: Candida albicans is the fourth most common cause of
nosocomial fungal infections across the world. The current drug regimens are suffering from …

The threat burden from pathogenic fungi is universal and increasing with alarming high
mortality and morbidity rates from invasive fungal infections. Understanding the virulence …

Callistemon lanceolatus (Myrtaceae) has been utilized in folk medicine and its
pharmacological properties are widely studied. Phytochemicals are effectively recognized …

During the last decade, Candida auris emerged as a threatening human fungal pathogen
that notably caused outbreaks around the globe with high mortality. Considering C. auris …

Aims Drug repurposing is an attractive chemotherapeutic strategy that serves to make up for
the inadequacy of current antifungal drugs. The present study aims to repurpose …