Oxygen as one of the most critical substances in living organisms has attracted ever‐
increasing attention in disease treatment, which is important in regulating metabolic …

Bacteria-mediated cancer therapy has become a topic of interest under the broad umbrella
of oncotherapy. Among many bacterial species, Salmonella remains at the forefront due to …

Many systemically administered cancer therapies exhibit dose-limiting toxicities that reduce
their effectiveness. To increase efficacy, bacterial delivery platforms have been developed …

Introduction The limitations of conventional cancer therapies necessitate target-oriented,
highly invasive, and safe treatment approaches. Hence, the intrinsic anti-tumor activity of …

Engineered microorganisms have attracted significant interest as a unique therapeutic
platform in tumor treatment. Compared with conventional cancer treatment strategies …

The stimulator of interferon genes (STING) protein is an important and promising innate
immune target for tumor therapy. However, the instability of the agonists of STING and their …

Emerging chemo-and radiotherapy resistance exacerbated the cancer risk and necessitated
novel treatment strategies. Although RNA therapeutics against pro-oncogenic genes are …

Breast cancer (BC) is a highly prevalent primary malignancy worldwide with poor prognosis.
Despite the development of aggressive interventions, mortality due to BC remains high. BC …

Bacteria have been explored for their potential in fighting against cancer for decades. Due to
their outstanding tumor‐targeting capacity and high biocompatibility, live bacteria can serve …

Modulating gene expression in macrophages can be used to improve tissue regeneration
and to redirect tumor microenvironments (TME) toward positive therapeutic outcomes. We …