T cell lymphoma and secondary primary malignancy risk after commercial CAR T cell therapy

G Ghilardi, JA Fraietta, JN Gerson, VM Van Deerlin… - Nature Medicine, 2024 - nature.com
We report a T cell lymphoma (TCL) occurring 3 months after anti-CD19 chimeric antigen
receptor (CAR) T cell immunotherapy for non-Hodgkin B cell lymphoma. The TCL was …

Diagnosis and initial treatment of transplant‐eligible high‐risk myeloma patients: a British Society for Haematology/UK Myeloma Society Good Practice Paper

M Kaiser, G Pratt, C Bygrave, K Bowles… - British Journal of …, 2024 - Wiley Online Library
Summary This Good Practice Paper provides recommendations for the diagnosis and initial
management of transplant‐eligible high‐risk myeloma patients. It describes recent updates …

Upfront or Deferred Autologous Stem Cell Transplantation for Newly Diagnosed Multiple Myeloma in the Era of Triplet and Quadruplet Induction and Minimal Residual …

CC Mo, MA Hartley-Brown, S Midha, PG Richardson - Cancers, 2023 - mdpi.com
Simple Summary Patients who are diagnosed with multiple myeloma are given an initial
sequence of treatments that usually, for those who are young and fit enough, includes high …

[PDF][PDF] Answering the “Doctor, can CAR-T therapy cause cancer?” question in clinic

R Banerjee, C Poh, AV Hirayama, J Gauthier… - Blood …, 2024 - ashpublications.org
COI notes: Competing interests: RB reports consulting: BMS, Caribou Biosciences,
Genentech, Janssen, Pfizer, Sanofi, SparkCures; Research: Novartis, Pack Health. CP …

Expert consensus on the incorporation of anti-CD38 monoclonal antibody therapy into the management of newly diagnosed multiple Myeloma

S Lonial, AD Bowser, A Chari, C Costello… - … Myeloma and Leukemia, 2023 - Elsevier
Multiple myeloma is a hematologic malignancy that is typically associated with recurrent
relapses. There are numerous frontline treatment regimens that are highly effective for …

The immunome of mobilized peripheral blood stem cells is predictive of long-term outcomes and therapy-related myeloid neoplasms in patients with multiple myeloma …

S Zanwar, EK Jacob, C Greiner, K Pavelko… - Blood cancer …, 2023 - nature.com
Upfront autologous stem cell transplant (ASCT) is the standard of care for newly diagnosed
multiple myeloma (MM) patients. However, relapse is ubiquitous and therapy-related …

Outcome of second primary malignancies developing in multiple myeloma patients

I Avivi, DH Vesole, J Davila-Valls… - Cancers, 2023 - mdpi.com
Simple Summary The emergence of new therapeutic agents for multiple myeloma (MM) over
the last 2 decades has resulted in a significant improvement in overall survival (OS) …

Single‐agent lenalidomide maintenance after upfront autologous stem cell transplant for newly diagnosed multiple myeloma: The MD Anderson experience

O Pasvolsky, DR Milton, A Masood… - American journal of …, 2023 - Wiley Online Library
The optimal duration of lenalidomide (Len) maintenance for patients with multiple myeloma
(MM) after autologous stem cell transplantation (autoHCT) is unknown. We conducted a …

Single versus tandem autologous stem cell transplantation in newly diagnosed multiple myeloma

N Grieb, A Oeser, M Ferle, F Hanke… - Bone Marrow …, 2024 - nature.com
Identifying patients who may benefit from autologous stem cell transplantation (ASCT) in
newly diagnosed multiple myeloma is crucial, especially in the era of effective induction and …

Characteristics and outcomes of patients with multiple myeloma who developed therapy-related acute myeloid leukemia and myelodysplastic syndrome after …

FF Yalniz, U Greenbaum, O Pasvolsky… - … and Cellular Therapy, 2024 - Elsevier
Patients with multiple myeloma (MM) who undergo high-dose chemotherapy and
autologous hematopoietic cell transplantation (Auto-HCT) have an increased risk of …