The evolution of resistance to traditional platinum-based anticancer drugs has compelled
researchers to investigate the cytostatic properties of alternative transition metal-based …

Numerous studies have shown that berberine and its derivatives demonstrate important anti-
tumor effects. However, the specific underlying mechanism remains unclear. Therefore …

Background/Aim: Cancer cells have an essential demand for vitamin B12 (cobalamin) to
enable cellular replication. The present pilot study quantified the immunohistochemical …

Nutrition may affect animal health due to the strong link between them. Also, diets improve
the healing process in various disease states. Cancer is a disease, where the harmful …

Cancer cells have an obligate need for cobalamin (vitamin B12) to enable DNA synthesis
necessary for cellular replication. This study quantified the immunohistochemical expression …

The synthesis, physico-chemical characterization and cytotoxicity against five human
tumoral cell lines (THP-1, U937, Molt-4, Colo205 and H460) of three new cobalt (II) …

The neuropeptide somatostatin (SST) plays an important regulatory role in the proliferation
of normal and neoplastic cells. Five subtypes of somatostatin receptors (SSTRs), SSTR1 …

This case report describes the diagnosis, management and outcome of three dogs with
peripheral nerve sheath tumors (PNSTs) involving the brachial plexus, C7 (case 1), C8 …

Abstract Nitrosylcobalamin (NO-Cbl), a novel vitamin B 12 analog and anti-tumor agent,
functions as a biologic 'Trojan horse', utilizing the vitamin B 12 transcobalamin II transport …

Summary Vitamin B12 (Cobalamin, Cbl) is a vital cofactor in many metabolic processes. For
Cbl assimilation and maintenance of Cbl homeostasis, humans have evolved a …