Actinic keratoses are dysplastic proliferations of keratinocytes with potential for malignant
transformation. Clinically, actinic keratoses present as macules, papules, or hyperkeratotic …

Keratinocyte carcinoma (KC) is the most common type of cancer among white populations,
but it is even more common among solid organ transplant recipients (OTRs). The most …

Immunosuppression commonly disrupts the homeostasis of mutated normal skin, leading to
widespread skin dysplasia and field cancerization. However, the immune system's role in …

The number of solid organ transplants has been increasing annually worldwide. Advances
in transplantation surgery and community awareness of organ donation have been key …

In the last two decades, the optimization of organ preservation and surgical techniques, and
the personalized immunosuppression have reduced the rate of acute rejections and early …

Cancer burden is increasing in kidney transplant recipients, but differences in mortality
compared to the general population remain unclear. We sought to compare cancer mortality …

Actinic keratosis (AK) is considered a chronic skin disease mostly caused by long-term
exposure to UV radiation and other risk factors such as immunosuppression, leading to an …

Background Keratinocyte carcinomas such as basal cell carcinomas and squamous cell
carcinomas are a major burden affecting morbidity and mortality in solid organ transplant …

Background Immunosuppressive drugs such as tacrolimus have revolutionized our ability to
transplant organs between individuals. Tacrolimus acts systemically to suppress the activity …

Importance: Skin cancer, in particular squamous cell carcinoma, is the most frequent
malignancy among solid organ transplant recipients with a higher incidence compared to …