A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases

W Zafar, SH Sumrra, ZH Chohan - European journal of medicinal chemistry, 2021 - Elsevier
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Pharmacological aspects of schiff base metal complexes: A critical review

T Ashraf, B Ali, H Qayyum, MS Haroone… - Inorganic Chemistry …, 2023 - Elsevier
Multidrug-resistant infections have placed a financial and health burden on the health-care
system and population. As a result, human health was faced major issues due to multidrug …

A review on the biomedical efficacy of transition metal triazole compounds

SH Sumrra, W Zafar, M Imran… - Journal of Coordination …, 2022 - Taylor & Francis
From the apocalyptic era of antibiotic resistance, the scientific community around the world is
engaged in designing and developing metal-based compounds to inhibit and control …

Metal incorporated aminothiazole-derived compounds: synthesis, density function theory analysis, in vitro antibacterial and antioxidant evaluation

SH Sumrra, Z Arshad, W Zafar… - Royal Society …, 2021 - royalsocietypublishing.org
The present study advocates the combined experimental and computational study of metal-
based aminothiazole-derived Schiff base ligands. The structure and electronic properties of …

A review on the antimicrobial assessment of triazole-azomethine functionalized frameworks incorporating transition metals

W Zafar, M Ashfaq, SH Sumrra - Journal of Molecular Structure, 2023 - Elsevier
Antimicrobial resistance is a growing threat to global public health that calls for innovative
strategies to develop new methods of action against resistance to emerging infectious …

Synthesis, structure elucidation, SC-XRD/DFT, molecular modelling simulations and DNA binding studies of 3,5-diphenyl-4,5-dihydro-1H-pyrazole chalcones

G Mustafa, S Sabir, SH Sumrra, W Zafar… - Journal of …, 2023 - Taylor & Francis
Deoxyribonucleic acid (DNA) acts as the most important intracellular target for various drugs.
Exploring the DNA binding interactions of small bioactive molecules offers a structural …

[HTML][HTML] Spectroscopic, anti-cancer, anti-bacterial and theoretical studies of new bivalent Schiff base complexes derived from 4-bromo-2, 6-dichloroaniline

TA Yousef, AS Al-Janabi - Heliyon, 2024 - cell.com
In this paper, four new mono-nuclear Ni (II), Pd (II), Pt (II) and Zn (II) complexes were
prepared by using a bi-dentate Schiff base ligand,(E)-2-(((4-bromo-2, 6-dichlorophenyl) …

Synthesis, characterization, antimicrobial, anticancer and the theoretical calculation of a novel N, O-multidentate chelating ligand and its Cu (II) and Fe (III) complexes

SS Hassan, SA Aly, NMH Rizk, MA Khidr… - Inorganic Chemistry …, 2024 - Elsevier
A new group of Cu (II) and Fe (III) complexes has been produced utilizing the ligand (Z)-N′-
(1-(thiophen-2-yl) ethylidene)-2-(p-tolylamino) acetohydrazide (H 2 L). The chemical …

Preparation, Antimicrobial Activity and Docking Study of Vanadium Mixed Ligand Complexes Containing 4-Amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol and …

D Domyati, SA Zabin, AA Elhenawy, M Abdelbaset - Processes, 2021 - mdpi.com
The synthesis of mixed-ligand complexes is considered an important strategy for developing
new metal complexes of enhanced biological activity. This paper presents the synthesis …

Synthesis, crystal structure, in vitro antifungal activity and molecular docking of 3-(1-((4H-1, 2, 4-triazol-4-yl) imino) ethyl)-2H-benzopyran-2-one derivatives

Y Feng, Y Hao, Y Dong, Y Ren, J Huang… - Journal of Molecular …, 2024 - Elsevier
Abstract Thirteen novel 3-(1-((4H-1, 2, 4-triazol-4-yl) imino) ethyl)-2H-benzopyran-2-one
derivatives (TEMC-1-TEMC-13) were synthesized. The structure of compounds were verified …