The high morbidity and mortality of non-small cell lung cancer (NSCLC) have always been
major threats to people's health. With the identification of carcinogenic drivers in non-small …

Lung cancer remains one of the major human malignancies affecting both men and women
worldwide, with non-small cell lung cancer (NSCLC) being the most prevalent type. Multiple …

Phosphatase and tensin homolog (PTEN) encodes a tumor-suppressive phosphatase with
both lipid and protein phosphatase activity. The tumor-suppressive functions of PTEN are …

Lysosomal-driven autophagy is a tightly controlled cellular catabolic process that breaks
down and recycles broken or superfluous cell parts. It is involved in several illnesses …

Osteosarcoma (OS) is a malignant bone carcinoma that affects people in childhood and
adulthood. The heterogeneous nature and chromosomal instability represent certain …

UPP1, a crucial pyrimidine metabolism-related enzyme, catalyzes the reversible
phosphorylation of uridine to uracil and ribose-1-phosphate. However, the effects of UPP1 in …

Cowden syndrome (CS) is a rare disease that was first described in 1963 and later included
in the large group of genodermatoses. It is the most common syndrome among the PTEN …

PTEN encodes a tumor suppressor with lipid and protein phosphatase activities whose
dysfunction has been implicated in melanomagenesis; less is known about how its …

Abstract Ethnopharmacological relevance Salvia miltiorrhiza Bunge is a kind of Chinese
herbal medicine known for activating blood circulation and removing blood stasis, with the …

Ischemic cardiomyopathy is treated mainly with thrombolytic drugs, percutaneous coronary
intervention, and coronary artery bypass grafting to recanalize blocked vessels. Myocardial …