Teaching an old dog new tricks: Drug discovery by repositioning natural products and their derivatives
B Huang, Y Zhang - Drug discovery today, 2022 - Elsevier
Highlights•Natural products show great promises in the drug repositioning campaign.•New
drug-disease associations are uncovered and discussed.•Pros and cons in natural product …
drug-disease associations are uncovered and discussed.•Pros and cons in natural product …
A tilted axis: maladaptive inflammation and HPA axis dysfunction contribute to consequences of TBI
Each year approximately 1.7 million people sustain a traumatic brain injury (TBI) in the US
alone. Associated with these head injuries is a high prevalence of neuropsychiatric …
alone. Associated with these head injuries is a high prevalence of neuropsychiatric …
Cognitive impairment and health-related quality of life following traumatic brain injury
N Gorgoraptis, J Zaw-Linn, C Feeney… - …, 2019 - content.iospress.com
BACKGROUND: Cognitive impairment is a common and disabling consequence of
traumatic brain injury (TBI) but its impact on health-related quality of life is not well …
traumatic brain injury (TBI) but its impact on health-related quality of life is not well …
The association between post-concussion symptoms and health-related quality of life in patients with mild traumatic brain injury
DC Voormolen, S Polinder, N Von Steinbuechel… - Injury, 2019 - Elsevier
A subset of mild traumatic brain injury (mTBI) patients experience post-concussion
symptoms. When a cluster of post-concussion symptoms persists for over three months, it is …
symptoms. When a cluster of post-concussion symptoms persists for over three months, it is …
[HTML][HTML] Sleep, sleep disorders, and mild traumatic brain injury. What we know and what we need to know: findings from a national working group
Disturbed sleep is one of the most common complaints following traumatic brain injury (TBI)
and worsens morbidity and long-term sequelae. Further, sleep and TBI share …
and worsens morbidity and long-term sequelae. Further, sleep and TBI share …
Effects of timing and intensity of neurorehabilitation on functional outcome after traumatic brain injury: a systematic review and meta-analysis
M Königs, EA Beurskens, L Snoep, EJ Scherder… - Archives of physical …, 2018 - Elsevier
Objective To systematically review evidence on the effects of timing and intensity of
neurorehabilitation on the functional recovery of patients with moderate to severe traumatic …
neurorehabilitation on the functional recovery of patients with moderate to severe traumatic …
Long-term outcome after severe traumatic brain injury: A systematic literature review
CQB Mostert, RD Singh, M Gerritsen… - Acta …, 2022 - Springer
Background Expectation of long-term outcome is an important factor in treatment decision-
making after severe traumatic brain injury (sTBI). Conclusive long-term outcome data …
making after severe traumatic brain injury (sTBI). Conclusive long-term outcome data …
Formyl peptide receptor 1 signaling in acute inflammation and neural differentiation induced by traumatic brain injury
Traumatic brain injury (TBI) is a shocking disease frequently followed by behavioral
disabilities, including risk of cerebral atrophy and dementia. N-formylpeptide receptor 1 …
disabilities, including risk of cerebral atrophy and dementia. N-formylpeptide receptor 1 …
Neuroprotective effect of artesunate in experimental model of traumatic brain injury
Traumatic brain injuries (TBI) are an important public health challenge. In addition,
subsequent events at TBI can compromise the quality of life of these patients. In fact, TBI is …
subsequent events at TBI can compromise the quality of life of these patients. In fact, TBI is …
Decompressive craniectomy for severe traumatic brain injury: a systematic review
Objective Systematic review of the literature to evaluate the role of decompressive
craniectomy (DC) after severe traumatic brain injury (TBI), comparing the first major …
craniectomy (DC) after severe traumatic brain injury (TBI), comparing the first major …