Collagen biosynthesis, processing, and maturation in lung ageing

C Onursal, E Dick, I Angelidis, HB Schiller… - Frontiers in …, 2021 - frontiersin.org
In addition to providing a macromolecular scaffold, the extracellular matrix (ECM) is a critical
regulator of cell function by virtue of specific physical, biochemical, and mechanical …

RAGE and its ligands: from pathogenesis to therapeutics

N Jangde, R Ray, V Rai - Critical reviews in biochemistry and …, 2020 - Taylor & Francis
Receptor for advanced glycation end products (RAGE) is an immunoglobulin-like receptor
present on cell surface. RAGE binds to an array of structurally diverse ligands, acts as a …

The axis of the receptor for advanced glycation endproducts in asthma and allergic airway disease

TN Perkins, ML Donnell, TD Oury - Allergy, 2021 - Wiley Online Library
Asthma is a generalized term that describes a scope of distinct pathologic phenotypes of
variable severity, which share a common complication of reversible airflow obstruction …

Small airways disease, biomarkers and COPD: where are we?

PS Chukowry, DA Spittle, AM Turner - International journal of …, 2021 - Taylor & Francis
The response to treatment and progression of Chronic Obstructive Pulmonary Disease
(COPD) varies significantly. Small airways disease (SAD) is being increasingly recognized …

LL-37 and HMGB1 induce alveolar damage and reduce lung tissue regeneration via RAGE

SD Pouwels, L Hesse, X Wu… - … of Physiology-Lung …, 2021 - journals.physiology.org
The receptor for advanced glycation end-products (RAGE) has been implicated in the
pathophysiology of chronic obstructive pulmonary disease (COPD). However, it is still …

RAGE and TLR4 differentially regulate airway hyperresponsiveness: Implications for COPD

VSRR Allam, A Faiz, M Lam, SNH Rathnayake, B Ditz… - Allergy, 2021 - Wiley Online Library
Background The receptor for advanced glycation end products (RAGE) and Toll‐like
receptor 4 (TLR4) is implicated in COPD. Although these receptors share common ligands …

The effects and pathogenesis of PM2. 5 and its components on chronic obstructive pulmonary disease

Q Wang, S Liu - … Journal of Chronic Obstructive Pulmonary Disease, 2023 - Taylor & Francis
Chronic obstructive pulmonary disease (COPD), a heterogeneous disease, is the leading
cause of death worldwide. In recent years, air pollution, especially particulate matter (PM) …

A systematic review and meta-analysis of the association of all types of beverages high in fructose with asthma in children and adolescents

F Keshavarz, M Zeinalabedini, S Ebrahimpour-Koujan… - BMC nutrition, 2024 - Springer
Background Asthma has become the most common chronic condition among children in
recent decades. Environmental factors, including food, drive its rise. Sweetened beverages …

Role of atypical chemokines and chemokine receptors pathways in the pathogenesis of COPD

F Nucera, F Lo Bello, SS Shen… - Current medicinal …, 2021 - ingentaconnect.com
Chronic obstructive pulmonary disease (COPD) represents a heightened inflammatory
response in the lung generally resulting from tobacco smoking-induced recruitment and …

Molecular clustering analysis of blood biomarkers in world trade center exposed community members with persistent lower respiratory symptoms

G Grunig, N Durmus, Y Zhang, Y Lu, S Pehlivan… - International journal of …, 2022 - mdpi.com
The destruction of the World Trade Center (WTC) on September 11, 2001 (9/11) released
large amounts of toxic dusts and fumes into the air that exposed many community members …