Abstract Loss of cadherin 1 (CDH1; also known as epithelial cadherin (E-cadherin)) is used
for the diagnosis and prognosis of epithelial cancers. However, it should not be ignored that …

Aberrant activation of Wnt signaling is involved in the development of several epithelial
tumors. Wnt signaling includes two major types of pathways:(i) the canonical or Wnt/β …

The transdifferentiation of epithelial cells toward a mesenchymal condition (EMT) is a
complex process that allows tumor cells to migrate to ectopic sites. Cadherins are not just …

Rationale: Long living individuals show delay of aging, which is characterized by the
progressive loss of cardiovascular homeostasis, along with reduced endothelial nitric oxide …

Thyroid carcinoma is a common malignant tumor of endocrine system and head and neck.
Recurrence, metastasis and high malignant expression after routine treatment are serious …

Endometrial cancer is often characterized by PI3K/AKT pathway deregulation. Recently it
has been suggested that SGK1, a serine/threonine protein kinase that shares structural and …

Objective To investigate immunologic parameters and endoplasmic reticulum (ER) stress
associated with unexplained infertility. Design Case-control study. Setting Academic center …

Modifications in adhesion molecules profile may change the way tumor cells interact with the
surrounding microenvironment. The Cadherin family is a large group of transmembrane …

Abstract Cadherin-16 (CDH16) plays a role in the embryonal development in kidney and
thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the thyroid. To …

Organization of epithelial cells during follicular lumen formation is crucial for thyroid
morphogenesis and function of the thyroid gland; however, the molecular mechanisms …