Electron transfer flavoprotein (ETF) is an enzyme with orthologs from bacteria to humans.
Human ETF is nuclear encoded by two separate genes, ETFA and ETFB, respectively. After …

Abstract NAD (P) H quinone oxidoreductase 1 (NQO1) is a multi-functional protein that
catalyses the reduction of quinones (and other molecules), thus playing roles in xenobiotic …

Protein misfolding has been linked to numerous inherited diseases. Loss‐and gain‐of‐
function mutations (common features of genetic diseases) may cause the destabilization of …

The approximately three times higher rate of migraine prevalence in women than men may
result from the mitochondrial transmission of this disease. Studies with imaging techniques …

Microglia chronic activation is a hallmark of several neurodegenerative diseases, including
the retinal ones, possibly contributing to their etiopathogenesis. However, some microglia …

Novel microbial strains capable of efficient degradation of TNT and typical intermediates (2-
ADNT and 4-ADNT) in aerobic/anaerobic environment were screened and isolated from …

Background Bipolar disorder is a chronic and often debilitating illness. Current treatment
options (both pharmaco-and psychotherapy) have shown efficacy, but for many leave a …

Objective Migraine is a common disease worldwide and migraine prevention is primarily
currently based on pharmaceuticals. The mechanism of Vitamin B2 may positively contribute …

In a 51-year-old patient of consanguineous parents with a severe neuromuscular phenotype
of early-onset ataxia, myoclonia, dysarthria, muscle weakness and exercise intolerance …

Human proteins are vulnerable towards disease-associated single amino acid replacements
affecting protein stability and function. Interestingly, a few studies have shown that …