Mitochondria are eukaryotic cellular organelles that function in energy metabolism, ROS
production, and programmed cell death. Cutaneous epithelial and hair follicle dermal papilla …

Persistent and unresolved inflammation is a common underlying factor observed in several
and seemingly unrelated human diseases, including cardiovascular and neurodegenerative …

Psoriasis is a chronic inflammatory skin disease featuring rapid proliferation of epidermal
cells. Although elevated glycolysis flux has been reported in psoriasis, the molecular …

Purpose To investigate the therapeutic effectiveness and safety of Janus kinase 1 inhibitor
upadacitinib in adolescent patients with atopic dermatitis (AD). Patients and Methods This …

Atopic dermatitis (AD) is a complex disease characterized by chronic recurring eczema and
pruritus. In addition, patients with AD display increased cutaneous and systemic levels of …

Mitochondria, as the “powerhouse” of eukaryotic cells, play the key role in central signalling
pathways decisive for the cell fate (proliferation, differentiation, growth and death) as well as …

Atopic dermatitis (AD) is a chronic disease in which epidermal barrier disruption triggers Th2-
mediated eruption of eczematous lesions. Topical emollients are a cornerstone of chronic …

Atopic dermatitis (AD) is a composite disease presenting disruption of the skin permeability
barrier (SPB) in the stratum corneum (SC). Recent evidence supports derangement of the …

Atopic dermatitis (AD) is a severe inflammatory skin disorder, characterized by elevated
levels of proinflammatory cytokines that fuel a vicious cycle of inflammation. While …

The epidermal barrier of mammals is initially formed during embryonic development and
continuously regenerated by the differentiation and cornification of keratinocytes in postnatal …