Synthesis, bioapplications, and toxicity evaluation of chitosan-based nanoparticles

BR Rizeq, NN Younes, K Rasool… - International journal of …, 2019 - mdpi.com
The development of advanced nanomaterials and technologies is essential in biomedical
engineering to improve the quality of life. Chitosan-based nanomaterials are on the forefront …

Skin barriers in dermal drug delivery: which barriers have to be overcome and how can we measure them?

C Gorzelanny, C Mess, SW Schneider, V Huck… - Pharmaceutics, 2020 - mdpi.com
Although, drugs are required in the various skin compartments such as viable epidermis,
dermis, or hair follicles, to efficiently treat skin diseases, drug delivery into and across the …

Amination-mediated nano eye-drops with enhanced corneal permeability and effective burst release for acute glaucoma treatment

DD Nguyen, CH Yao, SJ Lue, CJ Yang, YH Su… - Chemical Engineering …, 2023 - Elsevier
The development of topical formulations with advanced functions to overcome the poor and
sluggish permeability/bioavailability of traditional eye drops into interior of the eye is …

Activation of TRPV1 by capsaicin-loaded CaCO3 nanoparticle for tumor-specific therapy

M Xu, J Zhang, Y Mu, MF Foda, H Han - Biomaterials, 2022 - Elsevier
Capsaicin is a natural non-toxic small molecular organic substance, which is often used
clinically to reduce inflammation and pain. Here, we report an acid-responsive CaCO 3 …

Preparation and application of chitosan-based fluorescent probes

S Lv, S Liang, J Zuo, S Zhang, D Wei - Analyst, 2022 - pubs.rsc.org
Biomass materials have abundant natural resources, renewability and good biochemical
compatibility, so biomass-based fluorescent materials prepared from biomass materials …

Lactobacillus rhamnosus attenuates Thai chili extracts induced gut inflammation and dysbiosis despite capsaicin bactericidal effect against the probiotics, a possible …

W Panpetch, P Visitchanakun, W Saisorn… - PLoS …, 2021 - journals.plos.org
Because of a possible impact of capsaicin in the high concentrations on enterocyte injury
(cytotoxicity) and bactericidal activity on probiotics, Lactobacillus rhamnosus L34 (L34) and …

Trans-cinnamaldehyde loaded chitosan based nanocapsules display antibacterial and antibiofilm effects against cavity-causing Streptococcus mutans

R Mu, H Zhang, Z Zhang, X Li, J Ji, X Wang… - Journal of Oral …, 2023 - Taylor & Francis
Background Dental caries is a multifactorial disease, and the bacteria such as Streptococcus
mutans (S. mutans) is one of the risk factors. The poor effect of existing anti-bacterial is …

A reevaluation of chitosan-decorated nanoparticles to cross the blood-brain barrier

H Cortés, S Alcalá-Alcalá, IH Caballero-Florán… - Membranes, 2020 - mdpi.com
The blood-brain barrier (BBB) is a sophisticated and very selective dynamic interface
composed of endothelial cells expressing enzymes, transport systems, and receptors that …

Capsaicin loaded solid SNEDDS for enhanced bioavailability and anticancer activity: in-vitro, in-silico, and in-vivo characterization

DA Bhagwat, PA Swami, SJ Nadaf… - Journal of …, 2021 - Elsevier
In this investigation, the fabrication of capsaicin loaded self nano emulsifying drug delivery
system (SNEDDS) was attempted to improve the effectiveness of capsaicin through the oral …

pH responsive antifouling and antibacterial multilayer films with Self-healing performance

X Hao, WH Wang, Z Yang, L Yue, H Sun… - Chemical Engineering …, 2019 - Elsevier
The settlement and growth of marine organism increased sharply with the ships in a static
environment, although the release rate of antibacterial agent decreased smoothly. Besides …