The dynamic epigenetic landscape directs gene expression patterns that dictate cellular
form and function, and drive the assembly of cells into tissues. The high degree of plasticity …

Osteosarcoma is a malignant primary tumor of bone, arising from transformed progenitor
cells with osteoblastic differentiation and osteoid production. While categorized as a rare …

Activating autologous stem cells after the implantation of biomaterials is an important
process to initiate bone regeneration. Although several studies have demonstrated the …

Stem cells sense and respond to their local dynamic mechanical niches, which further
regulate the cellular behaviors. While in naturally, instead of instantly responding to real …

DNA microarrays are used to examine changes in gene expression of a large number of
genes simultaneously by fluorescent labeling of complementary DNAs (cDNAs). The major …

Following the consolidation of therapeutic proteins in the fight against cancer, autoimmune,
and neurodegenerative diseases, recent advancements in biochemistry and biotechnology …

The extracellular matrix (ECM) is thought to play a critical role in the progression of breast
cancer. In this work, we have designed a photopolymerizable, biomimetic synthetic matrix for …

Gastrulation is a stage in embryo development where three germ layers arise to dictate the
human body plan. In vitro models of gastrulation have been demonstrated by treating …

Bio-artificial kidneys require conveniently synthesized membranes providing signals that
regulate renal epithelial cell function. Therefore, we aimed to find synthetic analogues for …

Peptide microarrays, comprising hundreds to thousands of different peptides on solid
supports in a spatially discrete pattern, are increasingly being used as high throughput …