Importance Necrobiotic xanthogranuloma (NXG) is a non–Langerhans cell histiocytosis
classically associated with paraproteinemia attributable to plasma-cell dyscrasias or …

Sarcoidosis is a systemic inflammatory disease of unknown etiology. The pathogenesis rests
on an aberrant T cell response to unidentified antigens in individuals predisposed by …

The majority of cases involving hypercalcemia in the setting of sarcoidosis are explained by
the overproduction of calcitriol by activated macrophages. Vitamin D takes part in the …

Current concepts regarding calcium metabolism and bone healt... : Current Opinion in
Pulmonary Medicine Current concepts regarding calcium metabolism and bone health in …

After the initial description of extrarenal synthesis of 1, 25-dihydroxyvitamin D (1, 25-(OH) 2
D) three decades ago, extensive progress has been made in unraveling the …

Glucocorticoid-induced osteoporosis (GIOP) is a frequently encountered and serious side
effect of glucocorticoid use. Bone loss leading to an increased risk for fracture occurs early in …

Sarcoidosis is a systemic inflammatory disease of unknown etiology. Kidney involvement in
sarcoidosis may be present in up 25–30% of cases. An early diagnosis and prompt …

Objectives Sarcoidosis is a multisystem granulomatous disease of unknown etiology that in
90% of cases affects the lungs. Calcium metabolism testing can be useful in diagnostics …

An Uncommon Cause of Severe Hypercalcemia: Vitamin D Supplementation in Sarcoidosis
Page 1 An Uncommon Cause of Severe Hypercalcemia: Vitamin D Supplementation in …

Abnormal calcium metabolism in sarcoidosis patients can lead to hypercalcemia,
hypercalciuria, and kidney stones. Hypercalcemia in sarcoidosis is usually due to increased …