Obesity-associated metabolic inflammation drives the development of insulin resistance and
type 2 diabetes, notably through modulating innate and adaptive immune cells in metabolic …

Multiple high-throughput omics techniques provide different angles on systematically
quantifying and studying metabolic regulation of cellular processes. However, an unbiased …

Functional oncogenic links between ErbB2 and ERRα in HER2+ breast cancer patients
support a therapeutic benefit of co-targeted therapies. However, ErbB2 and ERRα also play …

Obesity is associated with chronic low-grade inflammation, also known as metabolic
inflammation, where continuous overnutrition generates a self-sustained inflammatory loop …

Activation of dendritic cells (DCs) for priming of T cell responses is dependent on rewiring of
their cellular metabolism. However, the metabolic characteristics of and requirements for …

Pro-longevity interventions such as caloric restriction (CR) and methionine restriction (MR)
can improve metabolic health. However, despite decades of extensive studies, the …

Abstract A Constitution Contested: Governors, Assemblies, and Imperial Politics in Jamaica
and New York, 1675-1730 Winston Sinclair Hill 2021 This dissertation focuses on the …