Nutriments have been deemed to impact all physiopathologic processes. Recent evidences
in molecular medicine and clinical trials have demonstrated that adequate nutrition …

Fasting mimicking diets (FMDs) are emerging as effective dietary interventions with the
potential to improve healthspan and decrease the incidence of cancer and other age-related …

Sperm motility is crucial to reproductive success in sexually reproducing organisms.
Impaired sperm movement causes male infertility, which is increasing globally. Sperm are …

Glycolytic intermediary metabolites such as fructose-1, 6-bisphosphate can serve as signals,
controlling metabolic states beyond energy metabolism. However, whether glycolytic …

Background More than ten randomized clinical trials are being tested to evaluate the
efficacy, effectiveness and safety of a fasting-mimicking diet (FMD) combined with different …

Multi‐component nanoparticles (mNPs) hold great potential for disease prevention and
treatment. However, a major barrier is the lack of versatile platforms to accommodate steps …

Diet, serving as a vital source of nutrients, exerts a profound influence on human health and
disease progression. Recently, dietary interventions have emerged as promising adjunctive …

In hepatocytes, peroxisome proliferator-activated receptor α (PPARα) orchestrates a
genomic and metabolic response required for homeostasis during fasting. This includes the …

Studies have found that intermittent fasting (IF) can prevent diabetes, cancer, heart disease,
and neuropathy, while in humans it has helped to alleviate metabolic syndrome, asthma …

In obesity, sustained adipose tissue (AT) inflammation constitutes a cellular memory that
limits the effectiveness of weight loss interventions. Yet, the impact of fasting regimens on …