Protective mechanisms of hypothermia in liver surgery and transplantation
PB Olthof, MJ Reiniers, MC Dirkes, TM van Gulik… - Molecular …, 2015 - Springer
Hepatic ischemia/reperfusion (I/R) injury is a side effect of major liver surgery that often
cannot be avoided. Prolonged periods of ischemia put a metabolic strain on hepatocytes …
cannot be avoided. Prolonged periods of ischemia put a metabolic strain on hepatocytes …
Hepatocellular carcinoma on cirrhosis complicated with tumoral thrombi extended to the right atrium: results in three cases treated with major hepatectomy and …
B Pesi, F Giudici, L Moraldi, G Montesi… - World Journal of …, 2016 - Springer
Background Hepatocellular carcinoma (HCC) with the presence of tumor thrombus in
hepatic veins and vena cava, until the atrium (RATT), is correlated with poor prognosis and …
hepatic veins and vena cava, until the atrium (RATT), is correlated with poor prognosis and …
[HTML][HTML] Warm ischemia time-dependent variation in liver damage, inflammation, and function in hepatic ischemia/reperfusion injury
Background Hepatic ischemia/reperfusion (I/R) injury is characterized by hepatocellular
damage, sterile inflammation, and compromised postoperative liver function. Generally used …
damage, sterile inflammation, and compromised postoperative liver function. Generally used …
[HTML][HTML] The damage-associated molecular pattern HMGB1 is released early after clinical hepatic ischemia/reperfusion
Objective and background Activation of sterile inflammation after hepatic
ischemia/reperfusion (I/R) culminates in liver injury. The route to liver damage starts with …
ischemia/reperfusion (I/R) culminates in liver injury. The route to liver damage starts with …
[HTML][HTML] Liver resection using total vascular exclusion of the liver preserving the caval flow, in situ hypothermic portal perfusion and temporary porta-caval shunt: a new …
Standard total vascular exclusion (TVE) of the liver is indicated for resection of tumors
involving or adjacent to the vena cava and/or the confluence of the hepatic veins. The …
involving or adjacent to the vena cava and/or the confluence of the hepatic veins. The …
The safety and feasibility of three-dimensional visualization technology assisted right posterior lobe allied with part of V and VIII Sectionectomy for right hepatic …
M Hu, H Hu, W Cai, Z Mo, N Xiang, J Yang… - … of Laparoendoscopic & …, 2018 - liebertpub.com
Background: Hepatectomy is the optimal method for liver cancer; the virtual liver resection
based on three-dimensional visualization technology (3-DVT) could provide better …
based on three-dimensional visualization technology (3-DVT) could provide better …
[HTML][HTML] Solutions to the discrepancies in the extent of liver damage following ischemia/reperfusion in standard mouse models
Due to their experimental versatility, mouse models are commonly used to study hepatic
ischemia/reperfusion (I/R) injury in relation to (I) the efficacy of surgical interventions [1],(II) …
ischemia/reperfusion (I/R) injury in relation to (I) the efficacy of surgical interventions [1],(II) …
[HTML][HTML] The physiology of artificial hibernation
MC Dirkes, TM van Gulik, M Heger - Journal of clinical and …, 2015 - ncbi.nlm.nih.gov
Incomplete understanding of the mechanisms responsible for induction of hibernation
prevent translation of natural hibernation to its artificial counterpart. To facilitate this …
prevent translation of natural hibernation to its artificial counterpart. To facilitate this …
Complex Hepatectomy Under Total Vascular Exclusion of the Liver Preserving the Caval Flow with Portal Hypothermic Perfusion and Temporary Portacaval Shunt: A …
D Azoulay, C Salloum, MA Allard, A Serrablo… - Annals of Surgical …, 2024 - Springer
Background Hypothermic liver perfusion decreases ischemia/reperfusion injury during
hepatectomy under standard total vascular exclusion (TVE) of the liver. This surgery needs …
hepatectomy under standard total vascular exclusion (TVE) of the liver. This surgery needs …
Hypothermic perfusion with retrograde outflow during right hepatectomy is safe and feasible
Background In situ hypothermic perfusion during liver resection performed under vascular
inflow occlusion decreases hepatic ischemia-reperfusion injury, but technical limitations …
inflow occlusion decreases hepatic ischemia-reperfusion injury, but technical limitations …