Abstract Purpose of Review Five years have passed since the World Health Organization
released its Global Technical Strategy for Malaria (GTS). In that time, progress against …

The∼ 30 Mb genomes of the Plasmodium parasites that cause malaria each encode∼
5000 genes, but the functions of the majority remain unknown. This is due to a paucity of …

The sexual phase of Plasmodium represents a crucial step in malaria transmission, during
which these parasites fertilize and form ookinetes to infect mosquitoes. Plasmodium …

Whole-sporozoite (WSp) malaria vaccines induce protective immune responses in animal
malaria models and in humans. A recent clinical trial with a WSp vaccine comprising …

Malaria as vector-borne disease remains important health concern with over 200 million
cases globally. Novel antimalarial medicines and more effective vaccines must be …

Gametocyte development is a critical step in the life cycle of Plasmodium. Despite the
number of studies on gametocyte development that have been conducted, the molecular …

The CRISPR/Cas9 system is a powerful genetic engineering technology for Plasmodium
falciparum. We here report further improvement of the CRISPR/Cas9 system by combining …

The use of fluorescent proteins (FPs) in Plasmodium parasites has been key to understand
the biology of this obligate intracellular protozoon. FPs like the green fluorescent protein …

Malaria‐causing parasites rely on an actin–myosin‐based motor for the invasion of different
host cells and tissue traversal in mosquitoes and vertebrates. The unusual myosin A of …

Plasmodium parasites, the causative agents of malaria, possess a complex lifecycle;
however, the mechanisms of gene regulation involved in the cell-type changes remain …