Photorespiration–Rubisco's repair crew

H Bauwe - Journal of Plant Physiology, 2023 - Elsevier
The photorespiratory repair pathway (photorespiration in short) was set up from ancient
metabolic modules about three billion years ago in cyanobacteria, the later ancestors of …

Inhibitors of succinate: quinone reductase/Complex II regulate production of mitochondrial reactive oxygen species and protect normal cells from ischemic damage but …

SJ Ralph, R Moreno-Sánchez, J Neuzil… - Pharmaceutical …, 2011 - Springer
Succinate: quinone reductase (SQR) of Complex II, occupying a unique central point in the
mitochondrial respiratory system as a major source of electrons driving reactive oxygen …

Using whole-exome sequencing to identify inherited causes of autism

WY Timothy, MH Chahrour, ME Coulter, S Jiralerspong… - Neuron, 2013 - cell.com
Despite significant heritability of autism spectrum disorders (ASDs), their extreme genetic
heterogeneity has proven challenging for gene discovery. Studies of primarily simplex …

Gene expression profiling gut microbiota in different races of humans

L Chen, YH Zhang, T Huang, YD Cai - Scientific reports, 2016 - nature.com
The gut microbiome is shaped and modified by the polymorphisms of microorganisms in the
intestinal tract. Its composition shows strong individual specificity and may play a crucial role …

[HTML][HTML] Ferrochelatase: mapping the intersection of iron and porphyrin metabolism in the mitochondria

CD Obi, T Bhuiyan, HA Dailey… - Frontiers in Cell and …, 2022 - frontiersin.org
Porphyrin and iron are ubiquitous and essential for sustaining life in virtually all living
organisms. Unlike iron, which exists in many forms, porphyrin macrocycles are mostly …

[FeFe]‐Hydrogenase: Defined Lysate‐Free Maturation Reveals a Key Role for Lipoyl‐H‐Protein in DTMA Ligand Biosynthesis

A Pagnier, B Balci, EM Shepard, H Yang… - Angewandte Chemie …, 2022 - Wiley Online Library
Abstract Maturation of [FeFe]‐hydrogenase (HydA) involves synthesis of a CO, CN−, and
dithiomethylamine (DTMA)‐coordinated 2Fe subcluster that is inserted into HydA to make …

Metaenzyme: Meta pan-enzyme learning for task-adaptive redesign

J Zheng, H Zhang, Q Xu, AP Zeng, SZ Li - Proceedings of the 32nd ACM …, 2024 - dl.acm.org
Enzyme design plays a crucial role in both industrial production and biology. However, this
field faces challenges due to the lack of comprehensive benchmarks and the complexity of …

Engineering Escherichia coli to produce branched-chain fatty acids in high percentages

GJ Bentley, W Jiang, LP Guamán, Y Xiao, F Zhang - Metabolic engineering, 2016 - Elsevier
Branched-chain fatty acids (BCFAs) are key precursors of branched-chain fuels, which have
cold-flow properties superior to straight chain fuels. BCFA production in Gram-negative …

Quantitative analysis of glycine related metabolic pathways for one-carbon synthetic biology

Y Hong, J Ren, X Zhang, W Wang, AP Zeng - Current opinion in …, 2020 - Elsevier
Glycine is an essential one-carbon (C1) metabolite nested in a complex network of cellular
metabolism. Glycine and its related metabolic pathways have important biochemical and …

Role of ammonia-lyases in the synthesis of the dithiomethylamine ligand during [FeFe]-hydrogenase maturation

A Pagnier, B Balci, EM Shepard, H Yang… - Journal of Biological …, 2024 - jbc.org
The generation of an active [FeFe]-hydrogenase requires the synthesis of a complex metal
center, the H-cluster, by three dedicated maturases: the radical S-adenosyl-l-methionine …